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伴有白细胞破碎性皮肤血管炎和低补体血症的免疫触须样肾小球病:一例报告

Immunotactoid glomerulopathy with leucocytoclastic skin vasculitis and hypocomplementemia: a case report.

作者信息

Schifferli J A, Merot Y, Cruchaud A, Chatelanat F

出版信息

Clin Nephrol. 1987 Mar;27(3):151-5.

PMID:3552344
Abstract

Immunotactoid glomerulopathy is a recently described entity characterized clinically by proteinuria, hematuria and hypertension, and on renal biopsy by various glomerular lesions including extracellular microtubules composed of immune reactants. Furthermore a defined immunological disease or cryoglobulinemia are absent. We report the case of a patient with immunotactoid glomerulopathy and hypocomplementemia (low C3 level) who developed several episodes of leucocytoclastic skin vasculitis with large immune deposits in and around small vessels. It is suggested that skin and renal involvement are part of the same systemic disease.

摘要

免疫触须样肾小球病是一种最近才被描述的疾病,其临床特征为蛋白尿、血尿和高血压,肾活检可见包括由免疫反应物构成的细胞外微管在内的各种肾小球病变。此外,不存在明确的免疫性疾病或冷球蛋白血症。我们报告了一例患有免疫触须样肾小球病和低补体血症(C3水平降低)的患者,该患者出现了几次白细胞破碎性皮肤血管炎发作,在小血管内及周围有大量免疫沉积物。提示皮肤和肾脏受累是同一系统性疾病的一部分。

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