Department of Geriatrics, The First Affiliated Hospital of China Medical University, No.155 Nanjing North Street, Shenyang, 110001, China.
Nutr J. 2022 May 6;21(1):25. doi: 10.1186/s12937-022-00782-0.
Abdominal aortic calcification (AAC) is recognized as a valuable predictor of cardiovascular diseases (CVDs). Dietary fiber is strongly correlated with CVDs. However, the effect of dietary fiber on AAC in the population is not well understood.
To assess the relationship between dietary fiber intake and AAC in the US adult population.
A total of 2671 individuals with both dietary fiber intake and AAC score data were enrolled from the 2013-2014 National Health and Nutrition Examination Survey (NHANES), a cross-sectional health examination in the US. Multinomial logistic regression was used to calculate the odds ratio (OR), with 95% confidence interval (CI). To reveal the relationship between dietary fiber intake and AAC, restricted cubic spline was also applied.
Out of the total participants, 241 (9%) had severe AAC and 550 (20%) had mild-moderate AAC. Multinomial logistic regression indicated that higher intake of dietary fiber was associated with lower risk of severe AAC, but not with lower risk of mild-moderate AAC. For every one standard deviation increase (9.4 g/day) in dietary fiber intake, the odds of severe AAC were reduced by 28% [OR 0.72 (95% CI, 0.57-0.90), p = 0.004], after adjusting for confounding factors. Dose-response relationship revealed that dietary fiber intake was negatively correlated with severe AAC (p for linear < 0.001, p for nonlinear = 0.695).
Dietary fiber intake was negatively associated with severe AAC, and showed a dose-response relationship in US adults.
腹主动脉钙化（AAC）被认为是心血管疾病（CVDs）的一个有价值的预测指标。膳食纤维与 CVDs 密切相关。然而，膳食纤维对人群中 AAC 的影响尚不清楚。
评估美国成年人膳食纤维摄入量与 AAC 之间的关系。
共纳入 2013-2014 年全国健康和营养调查（NHANES）中同时具有膳食纤维摄入量和 AAC 评分数据的 2671 名个体，这是美国一项横断面健康检查。使用多项逻辑回归计算比值比（OR）及其 95%置信区间（CI）。为了揭示膳食纤维摄入量与 AAC 之间的关系，还应用了限制立方样条。
在所有参与者中，241 人（9%）患有严重 AAC，550 人（20%）患有轻中度 AAC。多项逻辑回归表明，膳食纤维摄入量较高与严重 AAC 的风险降低相关，但与轻中度 AAC 的风险降低无关。膳食纤维摄入量每增加一个标准差（9.4 g/天），严重 AAC 的几率降低 28%[OR 0.72（95%CI，0.57-0.90），p=0.004]，校正混杂因素后。剂量反应关系显示，膳食纤维摄入量与严重 AAC 呈负相关（p 线性<0.001，p 非线性=0.695）。
膳食纤维摄入量与严重 AAC 呈负相关，并且在美国成年人中呈剂量反应关系。
