School of Chemical and Material Engineering, Jiangnan University, 1800 Lihu Road, Wuxi, 214122, China.
Mikrochim Acta. 2022 May 7;189(6):215. doi: 10.1007/s00604-022-05300-x.
Magnetic molecularly imprinted nanoparticles (MMINPs) were obtained with a one-step process through miniemulsion self-assembly using an amphiphilic random copolymer as both an emulsifier and MMINP coating, oleic acid-modified magnetite nanoparticles as magnetic cores, and melamine (MEL) as the template molecule. MMINPs were assembled under an external magnetic field to construct photonic crystal (PC) sensor for naked-eye detection of MEL. The MMINPs were characterized by FT-IR, TEM, TGA, and VSM. The analytical performances of the magnetic molecularly imprinted PC sensor for MEL (MEL-MMIPCs) were investigated with respect to sensitivity, response time, selectivity, and stability. As the MEL concentration increases from 1.0 to 1.0 × 10 μg/l, the reflection wavelength of MEL-MMIPCs shifted from 497 to 709 nm, and was linear with the logarithm of MEL concentration in this range. The detection limit was 0.21 μg/l (S/N = 3) and response time was within 30 s. The MEL-MMIPC sensor had an imprinting factor of 5.09, and selectivity factors for the analogs cyanuric acid and atrazine were 8.76 and 5.75, respectively, indicating the high sensitivity and selectivity. After 10 cycles of elution/response, MEL-MMIPCs still had a good ability to recognize MEL.
磁性分子印迹纳米粒子（MMINPs）通过使用两亲性无规共聚物作为乳化剂和 MMINP 涂层、油酸修饰的磁铁矿纳米颗粒作为磁性核，以及三聚氰胺（MEL）作为模板分子的 miniemulsion 自组装，以一步法获得。MMINPs 在外部磁场下组装，构建用于 MEL 的肉眼检测的光子晶体（PC）传感器。通过 FT-IR、TEM、TGA 和 VSM 对 MMINPs 进行了表征。研究了磁性分子印迹 PC 传感器对 MEL（MEL-MMIPCs）的分析性能，包括灵敏度、响应时间、选择性和稳定性。随着 MEL 浓度从 1.0 增加到 1.0×10μg/l，MEL-MMIPCs 的反射波长从 497nm 移动到 709nm，并且在该范围内与 MEL 浓度的对数呈线性关系。检测限为 0.21μg/l（S/N=3），响应时间在 30s 内。MEL-MMIPC 传感器的印迹因子为 5.09，对类似物氰尿酸和莠去津的选择性因子分别为 8.76 和 5.75，表明其具有较高的灵敏度和选择性。经过 10 次洗脱/响应循环后，MEL-MMIPCs 仍然具有良好的识别 MEL 的能力。
