Ding He, Lv Guoqing, Cai Xue, Chen Junyu, Cheng Ziyi, Peng Yanxiu, Tang Guo, Shi Zhao, Xie Yang, Fu Xin, Yin Lan, Yang Jian, Wang Yongtian, Sheng Xing
Beijing Engineering Research Center of Mixed Reality and Advanced Display, School of Optics and Photonics, Beijing Institute of Technology, Beijing, 100081, China.
Department of Electronic Engineering, Beijing National Research Center for Information Science and Technology, Institute for Precision Medicine, Center for Flexible Electronics Technology, and IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing, 100084, China.
Light Sci Appl. 2022 May 7;11(1):130. doi: 10.1038/s41377-022-00825-5.
Thermometric detectors are crucial in evaluating the condition of target objects spanning from environments to the human body. Optical-based thermal sensing tools have received extensive attention, in which the photon upconversion process with low autofluorescence and high tissue penetration depth is considered as a competent method for temperature monitoring, particularly in biomedical fields. Here, we present an optoelectronic thermometer via infrared-to-visible upconversion, accomplished by integrated light receiving and emission devices. Fully fabricated thin-film, microscale devices present temperature-dependent light emission with an intensity change of 1.5% °C and a spectral shift of 0.18 nm °C. The sensing mechanism is systematically characterized and ascribed to temperature dependent optoelectronic properties of the semiconductor band structure and the circuit operation condition. Patterned device arrays showcase the capability for spatially resolved temperature mapping. Finally, in vitro and in vivo experiments implemented with integrated fiber-optic sensors demonstrate real-time thermal detection of dynamic human activity and in the deep brain of animals, respectively.
温度探测器在评估从环境到人体等目标物体的状况方面至关重要。基于光学的热传感工具受到了广泛关注，其中具有低自发荧光和高组织穿透深度的光子上转换过程被认为是一种用于温度监测的有效方法，特别是在生物医学领域。在此，我们展示了一种通过红外到可见光上转换的光电温度计，它由集成的光接收和发射器件实现。完全制造的薄膜微尺度器件呈现出与温度相关的发光，强度变化为1.5%/°C，光谱位移为0.18nm/°C。对传感机制进行了系统表征，并归因于半导体能带结构的温度相关光电特性和电路工作条件。图案化的器件阵列展示了空间分辨温度映射的能力。最后，使用集成光纤传感器进行的体外和体内实验分别证明了对动态人体活动和动物深部大脑的实时热检测。
