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[Clinical features of severe acute respiratory syndrome coronavirus 2 Omicron variant infection in children: an analysis of 201 cases].儿童严重急性呼吸综合征冠状病毒2奥密克戎变异株感染的临床特征：201例分析
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本文引用的文献

1
Omicron mutations enhance infectivity and reduce antibody neutralization of SARS-CoV-2 virus-like particles.奥密克戎突变增强了 SARS-CoV-2 病毒样颗粒的感染力，并降低了抗体的中和作用。
Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2200592119. doi: 10.1073/pnas.2200592119. Epub 2022 Jul 19.
2
Structural diversity of the SARS-CoV-2 Omicron spike.SARS-CoV-2 奥密克戎刺突的结构多样性。
Mol Cell. 2022 Jun 2;82(11):2050-2068.e6. doi: 10.1016/j.molcel.2022.03.028. Epub 2022 Mar 25.
3
Increased risk of SARS-CoV-2 reinfection associated with emergence of Omicron in South Africa.南非出现奥密克戎后，SARS-CoV-2 再感染的风险增加。
Science. 2022 May 6;376(6593):eabn4947. doi: 10.1126/science.abn4947.
4
Neutralization of SARS-CoV-2 Omicron BA.2 by Therapeutic Monoclonal Antibodies.治疗性单克隆抗体对新冠病毒奥密克戎BA.2的中和作用
bioRxiv. 2022 Feb 24:2022.02.15.480166. doi: 10.1101/2022.02.15.480166.
5
Shorter serial intervals in SARS-CoV-2 cases with Omicron BA.1 variant compared with Delta variant, the Netherlands, 13 to 26 December 2021.与德尔塔变异株相比，奥密克戎 BA.1 变异株引起的 SARS-CoV-2 病例的连续间隔时间更短，荷兰，2021 年 12 月 13 日至 26 日。
Euro Surveill. 2022 Feb;27(6). doi: 10.2807/1560-7917.ES.2022.27.6.2200042.
6
Role of Omicron variant of SARS-CoV-2 in children in Germany.新冠病毒奥密克戎变异株在德国儿童中的作用。
World J Pediatr. 2022 Apr;18(4):283-284. doi: 10.1007/s12519-021-00511-3. Epub 2022 Feb 1.
7
Convulsions in children with COVID-19 during the Omicron wave.奥密克戎变异株流行期间儿童 COVID-19 相关惊厥
Acta Paediatr. 2022 May;111(5):1023-1026. doi: 10.1111/apa.16276. Epub 2022 Feb 10.
8
SARS-CoV-2 Omicron spike glycoprotein receptor binding domain exhibits super-binder ability with ACE2 but not convalescent monoclonal antibody.SARS-CoV-2 奥密克戎刺突糖蛋白受体结合域对 ACE2 表现出超强结合能力，但与恢复期单克隆抗体不结合。
Comput Biol Med. 2022 Mar;142:105226. doi: 10.1016/j.compbiomed.2022.105226. Epub 2022 Jan 7.
9
Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa.南非 SARS-CoV-2 奥密克戎变异株的快速流行扩张。
Nature. 2022 Mar;603(7902):679-686. doi: 10.1038/s41586-022-04411-y. Epub 2022 Jan 7.
10
Comparison of outcomes from COVID infection in pediatric and adult patients before and after the emergence of Omicron.奥密克戎出现前后儿童和成人患者新冠感染结局的比较。
medRxiv. 2022 Jan 2:2021.12.30.21268495. doi: 10.1101/2021.12.30.21268495.

加强儿童奥密克戎感染的防治

[Strengthening the prevention and treatment of Omicron infection in children].

作者信息

Jiao Fu-Yong, Ma Lei

机构信息

Shaanxi Provincial Clinical Research Center for Pediatric Diseases, Children's Hospital of Shaanxi Provincial People's Hospital, Xi'an 710068, China.

出版信息

Zhongguo Dang Dai Er Ke Za Zhi. 2022 Apr 15;24(4):345-349. doi: 10.7499/j.issn.1008-8830.2201001.

DOI:10.7499/j.issn.1008-8830.2201001
PMID:35527405
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9044981/
Abstract

Omicron is a newly discovered variant virus of coronavirus disease 2019 and has spread rapidly around the world. Omicron has been defined as a variant of concern by the World Health Organization. Its epidemiology, pathogenic characteristics, clinical diagnosis, treatment, and prevention are still being observed and summarized, and in particular, there are few reports on the diagnosis and treatment of children with Omicron infection. This article introduces the influence of Omicron infection in children and its prevention, diagnosis, and treatment.

摘要

奥密克戎是新发现的2019冠状病毒病变异病毒，已在全球迅速传播。奥密克戎已被世界卫生组织定义为值得关注的变异株。其流行病学、致病特征、临床诊断、治疗及预防仍在观察总结中，尤其是关于儿童感染奥密克戎的诊断和治疗报道较少。本文介绍了奥密克戎感染对儿童的影响及其预防、诊断和治疗。