Wang Y, Xiao L M, Yan H S, Yang Y P, Wang L L, Zhang H
Department of Otolaryngology, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China.
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2022 Apr 7;57(4):474-478. doi: 10.3760/cma.j.cn115330-20210622-00365.
To analyze the characteristics of allergen spectrum in patients with allergic rhinitis (AR) in Xinjiang area in recent 13 years. The skin prick test (SPT) results of 5 019 AR patients from 2007 to 2019 were retrospectively summarized, and 14 allergens of different age, gender and race were analyzed. The distribution of 14 allergens was significantly different in different years, the difference was significant (<0.05). The top three positive rates of 14 allergens were quinoa 48.2% (2 398/4 970), plantain 33.3% (1 221/3 667), and Artemisia 33.1% (1 647/4 974). There was no significant difference in the positive rate of dog epithelium between different genders and ages (χ²=0.041, >0.05; χ²=3.8, >0.05), the difference of other allergen in positive rates was statistically significant (all <0.05). The positive rates of Alternaria Alternata (7.3), Penicillium . (0.3), Cat Epithelium (3.1), Dust Mite (1.4), Acaroid Mite (0.5) and Cockroach (2.9) had no significant difference among different races (all >0.05). The positive rates of other eight allergens including Artemisia Vulgaris (64.9), Chenopodium (204.1), Artemisiifolia (72.4), Plantain (87.8), Phleum Pratense L(55.4), Robinia Pseudoacacia (67.8), Canis Familiari (70.8), Dog Epithelium (15.7) were significantly different among different races (all <0.05). The distribution of allergens in Xinjiang area changes with time, the main allergens are mainly herbaceous, and the distribution of allergens in patients with AR is different in gender, age and race.
分析新疆地区近13年变应性鼻炎（AR）患者变应原谱特征。回顾性总结2007年至2019年5019例AR患者的皮肤点刺试验（SPT）结果，分析14种不同年龄、性别和种族的变应原。14种变应原在不同年份的分布差异有统计学意义（<0.05）。14种变应原阳性率前三位的是藜麦48.2%（2398/4970）、车前草33.3%（1221/3667）、蒿属33.1%（1647/4974）。不同性别和年龄间犬上皮阳性率差异无统计学意义（χ²=0.041，>0.05；χ²=3.8，>0.05），其他变应原阳性率差异有统计学意义（均<0.05）。不同种族间链格孢（7.3）、青霉（0.3）、猫上皮（3.1）、尘螨（1.4）、粉螨（0.5）、蟑螂（2.9）阳性率差异无统计学意义（均>0.05）。其他8种变应原包括艾蒿（64.9）、藜（204.1）、豚草（72.4）、车前草（87.8）、梯牧草（55.4）、刺槐（67.8）、家犬（70.8）、犬上皮（15.7）在不同种族间阳性率差异有统计学意义（均<0.05）。新疆地区变应原分布随时间变化，主要变应原以草本为主，AR患者变应原分布在性别、年龄和种族上存在差异。
