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一名服用双膦酸盐的老年患者双侧股骨颈同时发生的不全骨折:病例报告及文献综述

Contemporaneous Insufficiency Fractures of Bilateral Femoral Necks in an Older Patient Taking Bisphosphonate: A Case Report and Literature Review.

作者信息

Tagomori Hiroaki, Kaku Nobuhiro, Sato Shota, Hosoyama Tsuguaki, Tsumura Hiroshi

机构信息

Department of Orthopedic Surgery, Faculty of Medicine, Oita University, 1-1 Idaigaoka Hasama-machi, Yufu City, Oita 879-5593, Japan.

出版信息

Case Rep Orthop. 2022 Apr 29;2022:9294289. doi: 10.1155/2022/9294289. eCollection 2022.

DOI:10.1155/2022/9294289
PMID:35528280
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9076345/
Abstract

We report, to the best of our knowledge, the first case of simultaneous insufficiency fracture of the bilateral femoral neck in an older patient taking bisphosphonate. Femoral neck fractures frequently occur in older individuals because of traumatic incidents, such as a fall. A 74-year-old woman with osteoporosis was taking raloxifene hydrochloride and bisphosphonate for approximately 5 and 3 years, respectively. Despite no history of falls or any other traumatic incidence, the patient reported cooccurrence of pain on both sides of the hip. Imaging revealed bilateral femoral neck fractures. Bipolar hemiarthroplasty and internal fixation were conducted on the right and left hips, respectively. At 6 months postoperatively, the patient reported gradual disappearance of left hip pain, and a radiograph revealed that the fracture had healed. Overall, clinical and histological findings suggested an atypical fracture, thereby proving that this type of fracture can occur in areas other than the femoral shaft.

摘要

据我们所知,我们报告了首例在服用双膦酸盐的老年患者中双侧股骨颈同时发生不全骨折的病例。股骨颈骨折在老年人中因创伤事件(如跌倒)而频繁发生。一名74岁患有骨质疏松症的女性分别服用盐酸雷洛昔芬和双膦酸盐约5年和3年。尽管没有跌倒史或任何其他创伤事件,但患者报告双侧臀部同时出现疼痛。影像学检查显示双侧股骨颈骨折。分别对右髋和左髋进行了双极半髋关节置换术和内固定术。术后6个月,患者报告左髋疼痛逐渐消失,X线片显示骨折已愈合。总体而言,临床和组织学检查结果提示为非典型骨折,从而证明这种类型的骨折可发生在股骨干以外的部位。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/103a/9076345/12355f0d2c52/CRIOR2022-9294289.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/103a/9076345/064812cf12fb/CRIOR2022-9294289.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/103a/9076345/f6031ff2578d/CRIOR2022-9294289.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/103a/9076345/7a045b7ab58a/CRIOR2022-9294289.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/103a/9076345/d6fd493392d5/CRIOR2022-9294289.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/103a/9076345/8913e263d2eb/CRIOR2022-9294289.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/103a/9076345/12355f0d2c52/CRIOR2022-9294289.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/103a/9076345/064812cf12fb/CRIOR2022-9294289.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/103a/9076345/f6031ff2578d/CRIOR2022-9294289.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/103a/9076345/7a045b7ab58a/CRIOR2022-9294289.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/103a/9076345/d6fd493392d5/CRIOR2022-9294289.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/103a/9076345/8913e263d2eb/CRIOR2022-9294289.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/103a/9076345/12355f0d2c52/CRIOR2022-9294289.006.jpg

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Bone. 2020 Aug;137:115453. doi: 10.1016/j.bone.2020.115453. Epub 2020 May 26.
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Periprosthetic atypical femoral fractures exist and are associated with duration of bisphosphonate therapy.假体周围非典型股骨骨折确实存在,并与双膦酸盐治疗时间相关。
Bone Joint J. 2019 Oct;101-B(10):1285-1291. doi: 10.1302/0301-620X.101B10.BJJ-2019-0599.R2.
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Unusual Bilateral Neck of Femur Stress Fracture in a Healthy, Non-athletic Individual - ACase Report and Literature Review.
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