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同步性肾细胞癌合并多发性骨髓瘤:椎体病变需评估而非臆断!

Synchronous RCC with multiple myeloma: vertebral lesion mandates evaluation not assumption!

作者信息

Hegde Abheesh Varma, Rao A Nagaraja, Choubey Suryakanth

机构信息

Department of Urology, Topiwala National Medical College & BYL Nair Ch. Hospital Dr. A Nair Road, Mumbai, India.

Department of Urology, Sapthagiri Institute of Medical Sciences & Research Hesaraghatta Road, Bangalore, India.

出版信息

Am J Clin Exp Urol. 2022 Apr 15;10(2):119-122. eCollection 2022.

PMID:35528462
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9077146/
Abstract

Vertebral lesions in patients with Renal Cell Carcinoma (RCC) are usually assumed to be metastatic. Synchronous malignancies are a rare occurrence. Association between Multiple myeloma (MM) and RCC has been described in the past. Common risk factors and similar cytokine growth requirements could be the linking factors. Here, we describe a patient who had RCC and on evaluation of the vertebral lesion, was found to have Multiple myeloma. We would like to highlight the fact that not all vertebral lesions in RCC are metastatic. Appropriate evaluation for the vertebral lesion would provide holistic treatment in such patients and improve outcomes.

摘要

肾细胞癌(RCC)患者的椎体病变通常被认为是转移性的。同时发生的恶性肿瘤很少见。过去曾描述过多发性骨髓瘤(MM)与RCC之间的关联。常见的风险因素和相似的细胞因子生长需求可能是联系因素。在此,我们描述了一名患有RCC的患者,在对椎体病变进行评估时,发现患有多发性骨髓瘤。我们想强调的是,并非所有RCC患者的椎体病变都是转移性的。对椎体病变进行适当评估将为这类患者提供全面治疗并改善预后。

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本文引用的文献

1
A patient with Multiple myeloma and Renal cell carcinoma.一名患有多发性骨髓瘤和肾细胞癌的患者。
Int J Hematol Oncol Stem Cell Res. 2016 Jan 1;10(1):56-60.
2
Coexistence of multiple myeloma and clear cell renal cell carcinoma: a case report and review of literature.多发性骨髓瘤与透明细胞肾细胞癌并存:一例报告并文献复习
Int J Clin Exp Pathol. 2015 Jun 1;8(6):7627-30. eCollection 2015.
3
Renal cell carcinoma and plasma cell myeloma: Unique association and clinical implications.肾细胞癌与浆细胞骨髓瘤:独特关联及临床意义
Urol Ann. 2014 Jul;6(3):252-6. doi: 10.4103/0974-7796.134292.
4
Synchronous renal cell carcinoma and multiple myeloma: report of two cases and review of the literature.同步性肾细胞癌与多发性骨髓瘤:两例报告并文献复习
J BUON. 2009 Jul-Sep;14(3):511-4.
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[Coincidence of multiple myeloma and renal clear cell adenocarcinoma].多发性骨髓瘤与肾透明细胞腺癌的巧合
Pol Arch Med Wewn. 2001 Feb;105(2):153-6.