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一名患有多发性骨髓瘤和肾细胞癌的患者。

A patient with Multiple myeloma and Renal cell carcinoma.

作者信息

Shahi Farhad, Ghalamkari Marziye, Mirzania Mehrzad, Khatuni Mahdi

机构信息

Department of Hematology and Medical Oncology, Cancer Research Center, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.

Internal Medicine Resident, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Int J Hematol Oncol Stem Cell Res. 2016 Jan 1;10(1):56-60.

PMID:27047652
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4818790/
Abstract

The coexistence of two malignancies is rarely seen. A little association between hematologic malignancies especially multiple myeloma and renal cell carcinoma has been reported in the recent past. Several case series revealed a bidirectional association between these two malignancies which may be due to the common risk factors, similar cytokine growth requirements and clinical presentation. Here, we aim to describe a patient who had multiple myeloma and in his work up renal cell carcinoma was found out incidentally. We would like to create awareness among clinicians for the coincidence of Renal cell carcinoma and Multiple myeloma.

摘要

两种恶性肿瘤并存的情况很少见。最近有报道称血液系统恶性肿瘤尤其是多发性骨髓瘤与肾细胞癌之间存在些许关联。几个病例系列显示这两种恶性肿瘤之间存在双向关联,这可能是由于共同的风险因素、相似的细胞因子生长需求和临床表现所致。在此,我们旨在描述一名患有多发性骨髓瘤的患者,在其检查过程中偶然发现了肾细胞癌。我们希望提高临床医生对肾细胞癌和多发性骨髓瘤并存情况的认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/602d/4818790/5686a61473e3/IJHOSCR-10-56-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/602d/4818790/2ec3f8224d2c/IJHOSCR-10-56-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/602d/4818790/67a289e84d1a/IJHOSCR-10-56-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/602d/4818790/5686a61473e3/IJHOSCR-10-56-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/602d/4818790/2ec3f8224d2c/IJHOSCR-10-56-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/602d/4818790/67a289e84d1a/IJHOSCR-10-56-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/602d/4818790/5686a61473e3/IJHOSCR-10-56-g003.jpg

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本文引用的文献

1
Renal cell carcinoma in patients with a personal or family history of hematologic malignancies.有个人或家族血液系统恶性肿瘤病史患者的肾细胞癌
Clin Adv Hematol Oncol. 2015 Jun;13(6):392-7.
2
Synchronous occurrence of prostate carcinoma and multiple myeloma: a case report.前列腺癌与多发性骨髓瘤同步发生:一例报告
Indian J Hematol Blood Transfus. 2014 Sep;30(Suppl 1):359-62. doi: 10.1007/s12288-014-0410-4. Epub 2014 Jun 1.
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Plasmablastic multiple myeloma following clear cell renal cell carcinoma.透明细胞肾细胞癌后发生的浆母细胞性多发性骨髓瘤。
BMJ Case Rep. 2014 Aug 6;2014:bcr2014204778. doi: 10.1136/bcr-2014-204778.
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The association between renal cell carcinoma and multiple myeloma: insights from population-based data.肾细胞癌与多发性骨髓瘤的相关性:基于人群数据的研究。
BJU Int. 2011 Sep;108(6):825-30. doi: 10.1111/j.1464-410X.2010.09892.x. Epub 2010 Nov 23.
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Clin Lymphoma Myeloma. 2008 Jun;8(3):188-90. doi: 10.3816/CLM.2008.n.025.
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Multiple myeloma and renal cell carcinoma possible association.多发性骨髓瘤与肾细胞癌可能存在关联。
Leuk Lymphoma. 2007 Aug;48(8):1662-4. doi: 10.1080/10428190701420442.
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Interleukin-6 produced by renal-cell carcinoma cells and progression of multiple myeloma.
N Engl J Med. 1991 Jun 27;324(26):1893-4. doi: 10.1056/NEJM199106273242613.