Antimicrobial Efficacy of Chlorhexidine and Herbal Mouth Rinse on Salivary in Children with Mixed Dentition: A Randomized Crossover Study.

AIM AND OBJECTIVE

() shows increased resistance to currently available antibiotics and chemotherapeutics. The present study compares the effectiveness of chlorhexidine and Herbal mouth rinse against salivary in children with mixed dentition.

MATERIALS AND METHODS

Subjects ( = 60) with mixed dentition were selected for the study. Caries status was recorded using Nyvard's criteria. Baseline saliva samples were collected and assessed for quantifying . Subjects were instructed to rinse their mouths with 0.2 % w/v chlorhexidine and herbal mouth rinse for 7 days. Saliva samples were collected after 7 days and assessed for . After a run-in period of 21 days, both the mouth rinses were crossed over according to the Latin square design, and a similar procedure was carried out. Later, determination of mean colony-forming units (CFU/mL) from the saliva samples was done. For statistical analysis, Kolmogorov and Mann-Whitney tests were applied.

RESULTS

Both the groups showed a significant reduction in count, at baseline and 7 days ( = 0.0001), and the reduction of count in herbal mouth rinse as compared to chlorhexidine mouth rinse ( = 0.0209) was statistically significant.

CONCLUSION

Herbal mouth rinse proved to have better antimicrobial efficacy than Chlorhexidine mouth rinse.

HOW TO CITE THIS ARTICLE

Shah SV, Badakar CM, Hugar SM, Antimicrobial Efficacy of Chlorhexidine and Herbal Mouth Rinse on Salivary Streptococcus mutans in Children with Mixed Dentition: A Randomized Crossover Study. Int J Clin Pediatr Dent 2022;15(1):99-103.