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槲皮素多聚糖苷的两亲性特性及pH依赖性胶束化作用

Bolaamphiphilic properties and pH-dependent micellization of quercetin polyglycoside.

作者信息

Nargis Mahmuda, Ihsan Abu Bin, Koyama Yasuhito

机构信息

Department of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University 5180 Kurokawa Imizu Toyama 939-0398 Japan

出版信息

RSC Adv. 2019 Oct 21;9(58):33674-33677. doi: 10.1039/c9ra05711k. eCollection 2019 Oct 18.

DOI:10.1039/c9ra05711k
PMID:35528900
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9073524/
Abstract

Quercetin polyglycoside as a new bolaamphiphile is prepared a one-pot grafting polymerization technique using sugar-based cyclic sulfite. Micelles comprising quercetin polyglycoside exhibit special pH-effects, in which the polyglycoside moieties on the surface of the micelle serve as a steric protecting group to endow chemical stabilization.

摘要

槲皮素多聚糖苷作为一种新型双亲性分子，通过一锅法接枝聚合技术，利用糖基环状亚硫酸盐制备而成。含有槲皮素多聚糖苷的胶束表现出特殊的pH效应，其中胶束表面的多聚糖苷部分作为空间保护基团赋予化学稳定性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2e6/9073524/195341b5557b/c9ra05711k-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2e6/9073524/ecc762d19de4/c9ra05711k-s1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2e6/9073524/965b9f4d9469/c9ra05711k-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2e6/9073524/412628f1be75/c9ra05711k-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2e6/9073524/872355faec20/c9ra05711k-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2e6/9073524/195341b5557b/c9ra05711k-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2e6/9073524/ecc762d19de4/c9ra05711k-s1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2e6/9073524/965b9f4d9469/c9ra05711k-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2e6/9073524/412628f1be75/c9ra05711k-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2e6/9073524/872355faec20/c9ra05711k-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2e6/9073524/195341b5557b/c9ra05711k-f4.jpg

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