槲皮素多聚糖苷的两亲性特性及pH依赖性胶束化作用
Bolaamphiphilic properties and pH-dependent micellization of quercetin polyglycoside.
作者信息
Nargis Mahmuda, Ihsan Abu Bin, Koyama Yasuhito
机构信息
Department of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University 5180 Kurokawa Imizu Toyama 939-0398 Japan
出版信息
RSC Adv. 2019 Oct 21;9(58):33674-33677. doi: 10.1039/c9ra05711k. eCollection 2019 Oct 18.
Abstract
Quercetin polyglycoside as a new bolaamphiphile is prepared a one-pot grafting polymerization technique using sugar-based cyclic sulfite. Micelles comprising quercetin polyglycoside exhibit special pH-effects, in which the polyglycoside moieties on the surface of the micelle serve as a steric protecting group to endow chemical stabilization.
摘要
槲皮素多聚糖苷作为一种新型双亲性分子，通过一锅法接枝聚合技术，利用糖基环状亚硫酸盐制备而成。含有槲皮素多聚糖苷的胶束表现出特殊的pH效应，其中胶束表面的多聚糖苷部分作为空间保护基团赋予化学稳定性。
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