Tasman W, Brown G C, Naidoff M, Schaffer D B, Benson W, Quinn G, Diamond G
Graefes Arch Clin Exp Ophthalmol. 1987;225(1):3-4. doi: 10.1007/BF02155794.
Twenty-eight patients with bilateral symmetrical stage-III retinopathy of prematurity and plus disease had one eye treated using cryotherapy, while the other acted as a control. Eleven patients showed improvement in both the treated and untreated eye, while 11 others were noted to improve in the treated eye while demonstrating deterioration in the untreated eye. The P value obtained by applying binomial distribution tests suggested that, in the sampled population, cryotherapy was preferable to no treatment.
28例患有双侧对称性Ⅲ期早产儿视网膜病变及附加病变的患儿,一只眼睛接受了冷冻疗法治疗,另一只眼睛作为对照。11例患儿的治疗眼和未治疗眼均有改善,另有11例患儿治疗眼有改善,但未治疗眼出现恶化。应用二项分布检验得到的P值表明,在抽样人群中,冷冻疗法优于不治疗。