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应用能谱 CT 碘水图对小肠出血进行定量评估。

Quantitative Evaluation of Small Intestinal Hemorrhage Using Energy Spectrum CT Iodine-Water Map.

机构信息

Radiographic Imaging Center, The Third Affiliated Hospital of Qiqihar Medical University, Qiqihar, 161000 Heilongjiang, China.

出版信息

Comput Math Methods Med. 2022 Apr 28;2022:9234579. doi: 10.1155/2022/9234579. eCollection 2022.

Abstract

The objective of this research is to analyze the quantitative evaluation of human small intestinal bleeding by observing and analyzing animal experiments of small intestinal hemorrhage in rabbit models for the convenience of understanding the role of energy spectrum CT iodine-water diagram in animal experimental research of quantitative evaluation of small intestinal bleeding in rabbit models. Compared with the energy spectrum of iodine-water graph of a rabbit CT model, the present study studied the quantitative evaluation of small intestinal bleeding by using a rabbit model instead of human. According to the method mentioned above and the analysis of experimental data, the role of energy spectrum CT iodine-water map and the quantitative evaluation of human small intestinal bleeding have been understood. It was found that the energy spectrum CT iodine-water map replaces humans in the rabbit model for quantitative evaluation of small intestinal bleeding in animal experiments, which is important in the present study. Besides, based upon the combination of theoretical and experimental data, the ten flow rates set on the base material iodine (water) maps of the arterial phase and the portal phase can be analyzed to detect the leakage of contrast agent. The yield was 100%. The research results showed that the animal experiment of quantitative assessment of small intestinal bleeding by replacing the human body with the rabbit model in the energy spectrum CT iodine-water diagram is critical to humans in the study of small intestinal hemorrhagic diseases. In addition, it can be used to adjust the treatment plan timely according to the amount of bleeding to prevent shock or heavy bleeding that threatens patients' lives.

摘要

本研究旨在通过观察和分析兔模型小肠出血的动物实验,分析人类小肠出血的定量评估,以便了解能谱 CT 碘水图在兔模型小肠出血定量评估动物实验研究中的作用。与兔 CT 模型碘水图的能谱相比,本研究采用兔模型代替人体研究了小肠出血的定量评估。根据上述方法和实验数据分析,了解了能谱 CT 碘水图和人体小肠出血定量评估的作用。结果发现,能谱 CT 碘水图在兔模型动物实验中代替人体对小肠出血进行定量评估,这在本研究中非常重要。此外,通过理论和实验数据的结合,可以对动脉期和门静脉期基础物质碘(水)图上设置的 10 个流速进行分析,以检测对比剂的泄漏。其产量为 100%。研究结果表明,能谱 CT 碘水图以兔模型代替人体进行小肠出血定量评估的动物实验对研究小肠出血性疾病的人类具有重要意义。此外,它可以根据出血量及时调整治疗方案,以防止休克或危及生命的大出血。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/305b/9071872/16811d7f11e0/CMMM2022-9234579.001.jpg

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