Yang Xiufang, Jiang Xulu, Wang Weitao, Yang Qi, Ma Yangmin, Wang Kuan
College of Chemistry & Chemical Engineering, Shaanxi University of Science & Technology Xi'an Shaanxi 710021 China
Shaanxi Key Laboratory of Chemical Additives for Industry, Shaanxi University of Science & Technology Xi'an Shaanxi 710021 China.
RSC Adv. 2019 Oct 25;9(59):34529-34534. doi: 10.1039/c9ra07201b. eCollection 2019 Oct 23.
A catalyst-free method for the hydroxylation of arylboronic acids to form the corresponding phenols with sodium perborate as the oxidant was developed using water as the solvent. Under the reaction conditions, the yield of phenol reached 92% at only 5 min. Moreover, the reaction could be conducted without a catalyst under the solvent-free condition, the efficiency of which was as high as that of a liquid-phase reaction. Using a microcalorimeter, the reaction was found to be an exothermic reaction. The reaction mechanism was investigated and understood DFT calculations, which revealed that it was a nucleophilic reaction.
开发了一种以水为溶剂、过硼酸钠为氧化剂将芳基硼酸羟基化以形成相应酚类的无催化剂方法。在该反应条件下，仅5分钟苯酚产率就达到了92%。此外，该反应在无溶剂条件下无需催化剂即可进行，其效率与液相反应一样高。使用微量热计，发现该反应是放热反应。通过密度泛函理论（DFT）计算对反应机理进行了研究并得到理解，结果表明这是一个亲核反应。
