Way Ashley, Ozdemir Savas, Berges Barbara, Getman Nataliya, Liang Xiaoying, Mendenhall Nancy P, Collins Graham, Cutter David, Mailhot Vega Raymond B
Department of Radiation Oncology, University of Florida College of Medicine, Jacksonville, FL, USA.
Department of Radiology, Division of Nuclear Medicine and Molecular Imaging, University of Florida College of Medicine, Jacksonville, FL, USA.
Int J Part Ther. 2021 Oct 18;8(4):76-81. doi: 10.14338/IJPT-21-00010. eCollection 2022 Spring.
We present a case of recurrent pericardial effusion presenting during proton therapy in a 24-year-old female receiving mediastinal treatment for classical Hodgkin lymphoma. Pericardial effusion is typically considered an event accompanying lymphoma diagnosis or as a subacute or late effect of radiotherapy. Rarely has it been described as occurring during radiation treatment with photon-based radiotherapy, let alone proton therapy. It is unclear what underlying cause triggered recurrent effusion in this patient. Identifying and managing pericardial effusion during treatment delivery is important to consider as it may affect radiation dosimetry, particularly with proton therapy. Doing so will help ensure patients receive optimal treatment and minimize the risks of morbidity and mortality.
我们报告了一例复发性心包积液病例，该病例发生在一名24岁接受纵隔经典型霍奇金淋巴瘤治疗的女性患者的质子治疗期间。心包积液通常被认为是淋巴瘤诊断时伴随的事件，或是放疗的亚急性或晚期效应。很少有报道称其发生在基于光子的放射治疗期间，更不用说质子治疗了。目前尚不清楚是什么潜在原因引发了该患者的复发性积液。在治疗过程中识别和处理心包积液很重要，因为它可能会影响放射剂量测定，尤其是质子治疗。这样做将有助于确保患者接受最佳治疗，并将发病和死亡风险降至最低。
