Li Chen, Chen Xian, Bao Rui-Peng, Li Dong-Li, Zhang Kun, Wang Dong-Hui
School of Biotechnology & Health Sciences, Wuyi University 22 Dongcheng Vill. Jiangmen Guangdong 529020 China
CAS Key Laboratory of Synthetic and Self-Assembly Chemistry for Organic Functional Molecules, Center for Excellence in Molecular Synthesis, University of Chinese Academy of Sciences, Shanghai Institute of Organic Chemistry, CAS 345 Lingling Rd. Shanghai 200032
RSC Adv. 2019 Sep 24;9(52):30134-30138. doi: 10.1039/c9ra06811b. eCollection 2019 Sep 23.
In this study, we demonstrate an Ir(iii)-catalyzed thioether directed alkenylation of arene C-H bonds under mild reaction conditions. The selectivity for mono- or di-alkenylation is controlled by the concentration of alkene and oxidant loading. Various functional groups are tolerated, and moderate to good yields of alkenylated products are achieved.
在本研究中，我们展示了在温和反应条件下铱（III）催化硫醚导向的芳烃C-H键烯基化反应。单烯基化或二烯基化的选择性由烯烃浓度和氧化剂负载量控制。该反应能耐受各种官能团，并获得了中等至良好产率的烯基化产物。
