Xie Yuan, Li Jinyang, Bu Daqin, Xie Xuedong, He Xiaolong, Wang Li, Zhou Zuowan
School of Materials Science and Engineering, Key Laboratory of Advanced Technologies of Materials (Ministry of Education), Southwest Jiaotong University Chengdu 610031 China
National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences Beijing 100101 China.
RSC Adv. 2019 Sep 4;9(48):27904-27910. doi: 10.1039/c9ra05198h. eCollection 2019 Sep 3.
In order to reduce the widespread threat of bacterial pathogen diseases, mechanical bactericidal surfaces have been widely reported. However, few of these nanostructured surfaces were investigated from a sustainable perspective. In this study, we have prepared, inspired by the slippery zone of , a multifunctional nanostructured surface with mechanical bactericidal, self-cleaning and insect anti-adhesive characteristics. First, a nanoblade-like surface made of Zn-Al layered double hydroxides was prepared for achieving faster bactericidal rate and wider bactericidal spectrum (2.10 × 10 CFU cm min against and 1.78 × 10 CFU cm min against ). Then the self-cleaning and insect anti-adhesive properties were tested on the fluorosilane-modified nanoblades, leaving little cell debris remaining on the surface even after 4 continuous bactericidal experiments, and showing a slippery surface for ants to slide down in 3 s. This study not only discovers a new nature-inspired mechanical bactericidal nanotopography, but also provides a facile approach to incorporate multiple functions into the nanostructured surface for practical antibacterial applications.
为了减少细菌病原体疾病的广泛威胁，机械杀菌表面已被广泛报道。然而，从可持续发展的角度对这些纳米结构表面进行研究的却很少。在本研究中，我们受[具体事物]的光滑区域启发，制备了一种具有机械杀菌、自清洁和昆虫抗粘附特性的多功能纳米结构表面。首先，制备了由锌铝层状双氢氧化物制成的纳米刀片状表面，以实现更快的杀菌速率和更宽的杀菌谱（对[具体细菌1]的杀菌速率为2.10×10 CFU cm⁻² min⁻¹，对[具体细菌2]的杀菌速率为1.78×10 CFU cm⁻² min⁻¹）。然后在氟硅烷改性的纳米刀片上测试了自清洁和昆虫抗粘附性能，即使经过4次连续杀菌实验后，表面仍几乎没有残留细胞碎片，并且对蚂蚁来说表面很光滑，能在3秒内滑落。本研究不仅发现了一种新的受自然启发的机械杀菌纳米形貌，还提供了一种将多种功能整合到纳米结构表面以用于实际抗菌应用的简便方法。
