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一例罕见的胰腺腺癌伴偶然发现的同步肝和乙状结肠转移病例报告及文献复习

A Rare Case of Pancreatic Adenocarcinoma With Incidental Synchronous Hepatic and Sigmoid Colonic Metastasis: A Case Report and Literature Review.

作者信息

AlAli Mohammed N, Ayesh Mohammed, Fathaddin Amany, AlQahtani Hamad

机构信息

General Surgery, King Khalid University Hospital, King Saud University, Riyadh, SAU.

Radiology, King Khalid University Hospital, King Saud University, Riyadh, SAU.

出版信息

Cureus. 2022 Apr 7;14(4):e23921. doi: 10.7759/cureus.23921. eCollection 2022 Apr.

Abstract

Metastasis of pancreatic adenocarcinoma to the colon is a very rare condition that might be underdiagnosed and underreported in the literature. We report a very rare case of incidental findings of sigmoid metastasis secondary to pancreatic adenocarcinoma in a 60-year-old Saudi male, who is a non-smoker with a normal medical and surgical history. The patient presented to a primary care clinic with abdominal bloating and vague on/off abdominal pain for almost 1 year as well as unintentional weight loss without lower gastrointestinal (GI) symptoms. After the case was discussed in the multidisciplinary tumor board, the patient was started on systematic palliative chemotherapy. However, after receiving the first cycle, he started to deteriorate rapidly and succumbed to secondary cardiopulmonary arrest. Cases of synchronous metastasis of pancreatic adenocarcinoma to the colon might not be well known or common. However, a high index of suspicion and individualizing the workup tools may need to be used.

摘要

胰腺腺癌转移至结肠是一种非常罕见的情况,在文献中可能存在诊断不足和报告不足的问题。我们报告了一例极为罕见的病例,一名60岁的沙特男性,非吸烟者,既往内科及外科病史均正常,偶然发现乙状结肠转移瘤继发于胰腺腺癌。患者因腹部胀痛、间歇性隐痛近1年且伴有非故意体重减轻,无下消化道症状,就诊于基层医疗诊所。在多学科肿瘤委员会讨论该病例后,患者开始接受系统性姑息化疗。然而,在接受第一个周期化疗后,他病情迅速恶化,最终因继发性心肺骤停死亡。胰腺腺癌同时转移至结肠的病例可能并不广为人知或常见。然而,可能需要高度怀疑并使用个体化的检查手段。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eee8/9076052/e3ad4730cc87/cureus-0014-00000023921-i01.jpg

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