Bethel Nyan, Asrar Henna, Dacosta Jenna, Savopoulos Andreas, Shaaban Hamid
Internal Medicine, Saint Michael's Medical Center, Newark, USA.
Hematology and Oncology, Saint Michael's Medical Center, Newark, USA.
Cureus. 2022 Apr 4;14(4):e23819. doi: 10.7759/cureus.23819. eCollection 2022 Apr.
Solitary plasmacytoma (SP) is characterized by an accumulation of neoplastic monoclonal plasma cells in a localized fashion, without evidence of multiple myeloma. It makes up <5% of all plasma cell neoplasms and is typically found in regions like the pelvis, ribs, vertebra, and spine. SP is classified into extramedullary plasmacytoma (EMP), which primarily affects soft tissues, and solitary bone plasmacytoma (SBP), which primarily affects the pelvis, ribs, vertebrae, and spine. We report a case of a 66-year-old man with sternal plasmacytoma presenting as chest pain. He was treated with radiation therapy. Here, we aim to describe the clinical features, diagnostic methods, treatment, and potential outcome in a patient with SBP.
孤立性浆细胞瘤(SP)的特征是肿瘤性单克隆浆细胞以局限性方式积聚,且无多发性骨髓瘤的证据。它占所有浆细胞肿瘤的比例不到5%,通常见于骨盆、肋骨、椎骨和脊柱等部位。SP分为主要影响软组织的髓外浆细胞瘤(EMP)和主要影响骨盆、肋骨、椎骨和脊柱的孤立性骨浆细胞瘤(SBP)。我们报告一例66岁男性胸骨浆细胞瘤患者,表现为胸痛。他接受了放射治疗。在此,我们旨在描述一名SBP患者的临床特征、诊断方法、治疗及潜在预后。