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关于双参数磁共振成像(bpMRI)在前列腺癌筛查、检测及总体准确性方面应用的叙述性综述。

A narrative review of biparametric MRI (bpMRI) implementation on screening, detection, and the overall accuracy for prostate cancer.

作者信息

Greenberg Jacob W, Koller Christopher R, Casado Crystal, Triche Benjamin L, Krane L Spencer

机构信息

Department of Urology, Tulane University School of Medicine, New Orleans, LA, USA.

Department of Radiology, Tulane University School of Medicine, New Orleans, LA, USA.

出版信息

Ther Adv Urol. 2022 May 4;14:17562872221096377. doi: 10.1177/17562872221096377. eCollection 2022 Jan-Dec.

Abstract

Prostate cancer is the most common malignancy in American men following skin cancer, with approximately one in eight men being diagnosed during their lifetime. Over the past several decades, the treatment of prostate cancer has evolved rapidly, so too has screening. Since the mid-2010s, magnetic resonance imaging (MRI)-guided biopsies or 'targeted biopsies' has been a rapidly growing topic of clinical research within the field of urologic oncology. The aim of this publication is to provide a review of biparametric MRI (bpMRI) utilization for the diagnosis of prostate cancer and a comparison to multiparametric MRI (mpMRI). Through single-centered studies and meta-analysis across all identified pertinent published literature, bpMRI is an effective tool for the screening and diagnosis of prostate cancer. When compared with the diagnostic accuracy of mpMRI, bpMRI identifies prostate cancer at comparable rates. In addition, when omitting dynamic contrast-enhanced (DCE) protocol to the MRI, patients incur reduced costs and shorter imaging time while providers can offer more tests to their patient population.

摘要

前列腺癌是美国男性继皮肤癌之后最常见的恶性肿瘤,约八分之一的男性在其一生中会被诊断出患有该病。在过去几十年里,前列腺癌的治疗方法迅速发展,筛查方法也是如此。自2010年代中期以来,磁共振成像(MRI)引导下的活检或“靶向活检”一直是泌尿肿瘤学领域临床研究中一个快速发展的话题。本出版物的目的是综述双参数MRI(bpMRI)在前列腺癌诊断中的应用,并与多参数MRI(mpMRI)进行比较。通过对所有已发表的相关文献进行单中心研究和荟萃分析,bpMRI是前列腺癌筛查和诊断的有效工具。与mpMRI的诊断准确性相比,bpMRI以相当的比率识别前列腺癌。此外,当在MRI中省略动态对比增强(DCE)方案时,患者的费用降低,成像时间缩短,而医疗服务提供者可以为更多患者提供检查。

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