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[石斛属植物化学成分及药理活性研究进展]

[Research advances in chemical constituents and pharmacological activities of Dendrobium plants].

作者信息

Zhao Ju-Run, Wang Yi-Han, Jin Yan, Jiang Chao, Zhan Zhi-Lai

机构信息

Institute of Caulis Dendrobii Longling County Baoshan 678300, China.

National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2022 May;47(9):2358-2372. doi: 10.19540/j.cnki.cjcmm.20220216.601.

Abstract

Dendrobii Caulis are commonly used tonic Chinese medicinal materials with a long history of application. As demonstrated by pharmacological results, the chemical constituents and the extracts of Dendrobii Caulis have anti-inflammatory, antibacte-rial, antioxidant, and anti-tumor effects, and can also regulate immunity, lower blood pressure, and regulate blood sugar. The active ingredients contained are widely concerned by scholars. This paper comprehensively summarized the chemical constituents and pharmacological activities of Dendrobium plants reported so far. The chemical constituents isolated from Dendrobium plants are mainly alkaloids, sesquiterpenoids, flavonoids, fluorenones, coumarins, bibenzyls, phenanthrenes, lignans, steroids, phenols, and polysaccharides. This paper is expected to provide a reference for further research, development, and utilization of Dendrobium plants.

摘要

石斛是常用的滋补中药材,应用历史悠久。药理结果表明,石斛的化学成分及提取物具有抗炎、抗菌、抗氧化、抗肿瘤作用,还能调节免疫、降血压和调节血糖。其所含的活性成分受到学者的广泛关注。本文全面总结了目前报道的石斛属植物的化学成分和药理活性。从石斛属植物中分离得到的化学成分主要有生物碱、倍半萜类、黄酮类、芴酮类、香豆素类、联苄类、菲类、木脂素类、甾体类、酚类和多糖类。本文有望为石斛属植物的进一步研究、开发和利用提供参考。

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