Trung Vuong Hospital, Ho Chi Minh City, Vietnam.
Faculty of Public Health, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam.
WHO South East Asia J Public Health. 2021 Jul-Dec;10(2):95-100. doi: 10.4103/WHO-SEAJPH.WHO_SEAJPH_149_21.
This study investigates the prevalence of and associated factors with depression and anxiety among chronic obstructive pulmonary disease (COPD) outpatients at Pham Ngoc Thach Hospital, Ho Chi Minh City, Vietnam. A cross-sectional study was conducted between March and May 2020 at the hospital's outpatient department. Those aged ≥18 years, diagnosed with COPD and undergoing COPD treatment, were eligible. The Hospital Anxiety and Depression Scale was used to measure depression and anxiety. Dyspnea was assessed using the modified Medical Research Council (mMRC) dyspnea scale. Among 392 patients, 381 (97%) participated in the study. The number of patients with depression and anxiety was 33.1% and 21.3%, respectively. Compared to men, women were more likely to experience depression (adjusted odds ratio [aOR] = 2.12, 95% confidence interval [CI] = 1.06-4.24) and anxiety (aOR = 4.11, 95% CI = 1.90-8.87). Those not having caregivers were more likely to experience depression (aOR = 3.03, 95% CI = 1.27-7.20) and anxiety (aOR = 3.47, 95% CI = 1.26-9.60). Having mMRC dyspnea scale ≥2 was associated with higher odds of experiencing depression (aOR = 5.94, 95% CI = 3.63-9.72) and anxiety (aOR = 6.78, 95% CI = 3.48-13.18). Those not adhering to medication treatment (aOR = 2.32, 95% CI = 1.15-4.70) and having comorbidity (aOR = 2.02, 95% CI = 1.10-3.73) were more likely to experience anxiety. Routine screening of COPD patients for depression and anxiety is necessary so that early interventions could be provided.
本研究调查了越南胡志明市范玉石医院慢性阻塞性肺疾病（COPD）门诊患者的抑郁和焦虑患病率及相关因素。这是一项 2020 年 3 月至 5 月在该医院门诊进行的横断面研究。年龄≥18 岁、被诊断为 COPD 并正在接受 COPD 治疗的患者符合条件。采用医院焦虑抑郁量表（HADS）评估抑郁和焦虑，采用改良医学研究委员会呼吸困难量表（mMRC）评估呼吸困难。在 392 名患者中，有 381 名（97%）参与了研究。患有抑郁和焦虑的患者分别占 33.1%和 21.3%。与男性相比，女性更易出现抑郁（调整后的优势比[aOR] = 2.12，95%置信区间[CI] = 1.06-4.24）和焦虑（aOR = 4.11，95% CI = 1.90-8.87）。没有护理者的患者更易出现抑郁（aOR = 3.03，95% CI = 1.27-7.20）和焦虑（aOR = 3.47，95% CI = 1.26-9.60）。mMRC 呼吸困难量表≥2 与出现抑郁的几率更高相关（aOR = 5.94，95% CI = 3.63-9.72）和焦虑（aOR = 6.78，95% CI = 3.48-13.18）。不遵医嘱治疗药物（aOR = 2.32，95% CI = 1.15-4.70）和合并症（aOR = 2.02，95% CI = 1.10-3.73）与焦虑的发生相关。有必要对 COPD 患者进行抑郁和焦虑的常规筛查，以便提供早期干预。
