College of Geography and Environmental Science, Henan University, Kaifeng, 475004, Henan, China.
Key Laboratory of Geospatial Technology for the Middle and Lower Yellow River Regions, Henan University, Kaifeng, 475004, Henan, China.
Environ Sci Pollut Res Int. 2022 Sep;29(45):68103-68117. doi: 10.1007/s11356-022-20592-5. Epub 2022 May 9.
A substantial number of studies have demonstrated the association between air pollution and adverse health effects. However, few studies have explored the potential interactive effects between meteorological factors and air pollution. This study attempted to evaluate the interactive effects between meteorological factors (temperature and relative humidity) and air pollution ([Formula: see text], [Formula: see text], [Formula: see text], and [Formula: see text]) on cardiovascular diseases (CVDs). Next, the high-risk population susceptible to air pollution was identified. We collected daily counts of CVD hospitalizations, air pollution, and weather data in Nanning from January 1, 2014, to December 31, 2015. Generalized additive models (GAMs) with interaction terms were adopted to estimate the interactive effects of air pollution and meteorological factors on CVD after controlling for seasonality, day of the week, and public holidays. On low-temperature days, an increase of [Formula: see text] in [Formula: see text], [Formula: see text], and [Formula: see text] was associated with increases of 4.31% (2.39%, 6.26%) at lag 2; 2.74% (1.65%, 3.84%) at lag 0-2; and 0.13% (0.02%, 0.23%) at lag 0-3 in CVD hospitalizations, respectively. During low relative humidity days, a [Formula: see text] increment of lag 0-3 exposure was associated with increases of 3.43% (4.61%, 2.67%) and 0.10% (0.04%, 0.15%) for [Formula: see text] and [Formula: see text], respectively. On high relative humidity days, an increase of [Formula: see text] in [Formula: see text] was associated with an increase of 5.86% (1.82%, 10.07%) at lag 0-2 in CVD hospitalizations. Moreover, elderly (≥ 65 years) and female patients were vulnerable to the effects of air pollution. There were interactive effects between air pollutants and meteorological factors on CVD hospitalizations. The risk that [Formula: see text], [Formula: see text], and [Formula: see text] posed to CVD hospitalizations could be significantly enhanced by low temperatures. For [Formula: see text] and [Formula: see text], CVD hospitalization risk increased in low relative humidity. The effects of [Formula: see text] were enhanced at high relative humidity.
大量研究表明，空气污染与不良健康影响之间存在关联。然而，很少有研究探讨气象因素与空气污染之间潜在的交互作用。本研究试图评估气象因素（温度和相对湿度）与空气污染（[Formula: see text]、[Formula: see text]、[Formula: see text]和[Formula: see text]）对心血管疾病（CVDs）的交互作用。接下来，确定了易受空气污染影响的高危人群。我们收集了 2014 年 1 月 1 日至 2015 年 12 月 31 日期间南宁市的 CVD 住院、空气污染和气象数据的每日数据。采用具有交互项的广义加性模型（GAMs），在控制季节性、星期几和节假日的情况下，估计空气污染和气象因素对 CVD 的交互作用。在低温天，[Formula: see text]浓度每增加[Formula: see text]，CVD 住院的滞后 2 期、0-2 期和 0-3 期的增长率分别为 4.31%（2.39%，6.26%）、2.74%（1.65%，3.84%）和 0.13%（0.02%，0.23%）。在低相对湿度天，[Formula: see text]暴露的滞后 0-3 期每增加[Formula: see text]，CVD 住院的增长率分别为 3.43%（4.61%，2.67%）和 0.10%（0.04%，0.15%）。在高相对湿度天，[Formula: see text]浓度每增加[Formula: see text]，CVD 住院的滞后 0-2 期的增长率为 5.86%（1.82%，10.07%）。此外，老年（≥65 岁）和女性患者易受空气污染影响。空气污染与气象因素对 CVD 住院率存在交互作用。低温可显著增强[Formula: see text]、[Formula: see text]和[Formula: see text]对 CVD 住院率的影响。对于[Formula: see text]和[Formula: see text]，CVD 住院风险在低相对湿度时增加。在高相对湿度时，[Formula: see text]的影响增强。
