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Interferons in COVID-19: missed opportunities to prove efficacy in clinical phase III trials?新冠疫情中的干扰素：错失在III期临床试验中证明疗效的机会？
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本文引用的文献

1
Specialized interferon action in COVID-19.新冠病毒中的干扰素作用机制。
Proc Natl Acad Sci U S A. 2022 Mar 15;119(11). doi: 10.1073/pnas.2116730119.
2
An open-label randomized controlled trial of the effect of lopinavir/ritonavir, lopinavir/ritonavir plus IFN-β-1a and hydroxychloroquine in hospitalized patients with COVID-19.一项关于洛匹那韦/利托那韦、洛匹那韦/利托那韦联合 IFN-β-1a 和羟氯喹对 COVID-19 住院患者疗效的开放性随机对照试验。
Clin Microbiol Infect. 2021 Dec;27(12):1826-1837. doi: 10.1016/j.cmi.2021.05.020. Epub 2021 May 26.
3
Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients.严重 COVID-19 患者的 I 型干扰素活性和炎症反应受损。
Science. 2020 Aug 7;369(6504):718-724. doi: 10.1126/science.abc6027. Epub 2020 Jul 13.

An open-label randomized, controlled trial of the effect of lopinavir and ritonavir, lopinavir and ritonavir plus interferon-β-1a, and hydroxychloroquine in hospitalized patients with COVID-19: final results.

作者信息

Ader Florence

出版信息

Clin Microbiol Infect. 2022 Sep;28(9):1293-1296. doi: 10.1016/j.cmi.2022.04.016. Epub 2022 May 7.

DOI:10.1016/j.cmi.2022.04.016
PMID:35533972
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9076583/
Abstract
摘要