Mitra Suvradeep, Geethanjali Gude, Rathi Sahaj, Behera Arunanshu, Das Ashim
1 Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
Int J Surg Pathol. 2018 Dec;26(8):739-744. doi: 10.1177/1066896918774843. Epub 2018 May 10.
Incidental intrahepatic cholangiocarcinoma (iCCA) is a rare neoplastic lesion in the explant liver specimens with an approximate incidence of 0.7%. The detection of iCCA is associated with poor prognosis in the posttransplant setting. The occurrence of a subcentimetric iCCA is very rare and poses a major diagnostic challenge to the pathologist. This article presents a rare case of subcentimetric iCCA in a young male in the background of advanced stage chronic liver disease resulting from autoimmune hepatitis possibly with chronic cholangiopathy along with the histomorphological differentials.
偶然发现的肝内胆管癌（iCCA）是移植肝标本中一种罕见的肿瘤性病变，发病率约为0.7%。在移植后情况下，iCCA的检出与预后不良相关。小于1厘米的iCCA的发生非常罕见，给病理学家带来了重大的诊断挑战。本文介绍了一例年轻男性中罕见的小于1厘米的iCCA病例，该病例发生在自身免疫性肝炎可能伴有慢性胆管病导致的晚期慢性肝病背景下，并伴有组织形态学鉴别诊断。
