Department of Anesthesiology and Intensive Care, Mersin University School of Medicine, Mersin, Turkey.
Department of General Surgery, Mersin University School of Medicine, Mersin, Turkey.
J Surg Oncol. 2022 Sep;126(3):425-432. doi: 10.1002/jso.26914. Epub 2022 May 10.
With the increasing rate of breast cancer surgery, the pain management of these patients gains importance. The aim of this study is to compare the ultrasound (US) guided thoracic paravertebral block (TPV) versus intraoperative pectoral nerve block (PECS) with a low volume local anaesthetic for postoperative analgesia after breast cancer surgery. A total of 41 patients underwent mastectomy and sentinel lymph node biopsy or modified radical mastectomy were included in this randomized controlled, single-blinded trial. The patients were divided into two groups as PECS and TPV blocks. In the PECS group, 10 ml of 0.5% bupivacaine was administered to the fascial plane by the surgeon. In the TPV group, 25 ml of 0.25% bupivacaine at T3 level was administered by the anaesthetist under US-guidance. Visual analogue scale (VAS) scores and additional analgesic requirements were recorded at postoperative 0, 6, 12, 24 and 48 h.
In the TPV group, mean VAS score (VAS0) was significantly lower (p ˂ 0.001). In other time periods, there was no significant difference between the groups.
It was observed that intraoperative PECS block was as effective as TPV in providing postoperative analgesia and additional analgesic requirements were similar. This result suggests PECS block may be a good alternative to TPV.
随着乳腺癌手术率的不断上升,这些患者的疼痛管理变得越来越重要。本研究旨在比较超声(US)引导下胸椎旁阻滞(TPV)与术中胸肌神经阻滞(PECS)在乳腺癌手术后的镇痛效果。共有 41 例接受乳腺癌改良根治术或保乳术和前哨淋巴结活检术的患者参与了这项随机对照、单盲试验。患者分为 PECS 组和 TPV 组。在 PECS 组,由外科医生在筋膜平面注射 10ml 0.5%布比卡因。在 TPV 组,麻醉医生在超声引导下于 T3 水平注射 25ml 0.25%布比卡因。记录术后 0、6、12、24 和 48 小时的视觉模拟评分(VAS)和额外镇痛需求。
TPV 组的平均 VAS 评分(VAS0)明显较低(p<0.001)。在其他时间段,两组之间无显著差异。
术中 PECS 阻滞与 TPV 一样有效,提供术后镇痛,额外镇痛需求相似。这一结果表明,PECS 阻滞可能是 TPV 的良好替代方法。