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改良胸大肌神经阻滞与双平面竖脊肌平面阻滞在乳腺癌根治术后镇痛中的比较:一项前瞻性、随机、对照试验。

Modified pectoral nerve block versus bi-level erector spinae plane block for postoperative analgesia after radical mastectomy surgery: a prospective, randomized, controlled trial.

机构信息

Department of Anesthesiology and Reanimation, Kocaeli University, Kocaeli, Turkey.

Department of General Surgery, Kocaeli University, Kocaeli, Turkey.

出版信息

Korean J Anesthesiol. 2023 Aug;76(4):317-325. doi: 10.4097/kja.22188. Epub 2023 Mar 14.

Abstract

BACKGROUND

Regional anesthesia techniques constitute an important part of successful analgesia strategies in the perioperative care of patients undergoing breast surgery. The advent of ultrasound-guided regional anesthesia has led to the development of fascial plane blocks. The large array of blocks available for postoperative analgesia in breast surgery has increased the accessibility of regional anesthesia but has also created a dilemma of choice. This study compared the analgesic efficacy of the ultrasound-guided modified pectoral nerve (PECS) block and erector spinae plane block (ESPB) in patients undergoing radical mastectomy.

METHODS

Seventy women were enrolled in this prospective, double-blind, randomized control trial. After exclusion, 67 female patients who underwent radical mastectomy were finally analyzed. Ultrasound-guided PECS blocks and ESPBs were performed with 30 ml 0.25% bupivacaine. Postoperative morphine and pain scores were compared between the groups.

RESULTS

Postoperative total morphine consumption in the first 24 h was significantly higher in the PECS group (P < 0.001). The ESPB group exhibited significantly reduced morphine consumption at all postoperative time points. Numeric rating scale scores were lower in the ESPB group at 6, 12, and 24 h postoperatively at rest and when coughing.

CONCLUSIONS

Ultrasound-guided bi-level ESPBs provided better postoperative analgesia than PECS blocks after radical mastectomy surgery.

摘要

背景

区域麻醉技术是成功进行乳房手术围手术期患者镇痛策略的重要组成部分。超声引导下区域麻醉的出现催生了筋膜平面阻滞。大量可用于乳房手术后镇痛的阻滞方法增加了区域麻醉的可及性,但也造成了选择上的困境。本研究比较了超声引导下改良胸肌神经(PECT)阻滞和竖脊肌平面阻滞(ESPB)在接受根治性乳房切除术患者中的镇痛效果。

方法

本前瞻性、双盲、随机对照试验共纳入 70 名女性。排除后,最终对 67 名接受根治性乳房切除术的女性患者进行了分析。采用 30ml0.25%布比卡因行超声引导下 PECT 阻滞和 ESPB。比较两组患者术后吗啡用量和疼痛评分。

结果

术后 24 小时内,PECT 组的总吗啡消耗量显著更高(P<0.001)。ESP 组在所有术后时间点的吗啡消耗量均显著减少。ESP 组在术后 6、12 和 24 小时静息和咳嗽时的数字评分量表评分均较低。

结论

超声引导下双平面 ESPB 比 PECT 阻滞在根治性乳房手术后提供了更好的术后镇痛效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/419f/10391080/1dfd3c0ad112/kja-22188f1.jpg

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