Wang N, Yin J X
School of Public Health, Dali University, Dali, Yunnan 671000, China.
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2021 Dec 14;34(2):200-203. doi: 10.16250/j.32.1374.2021163.
Hemorrhagic fever with renal syndrome (HFRS) is a category B infectious disease caused by hantaviruses that cause acute kidney injury and has a high mortality rate, and HFRS control has been given a high priority in China. It has been found that hantavirus types are closely associated with selective host transformation and regional adaption, and continue to evolve in the form of gene recombination. The severity of HFRS varies in hantavirus types. In addition, global environmental changes and alteration of host animal behaviors accelerate Hantavirus genome variations, and large-scale land reclamation and infrastructure building increases the likelihood of human contacts with hosts and disease-transmitting vectors, thereby increasing the risk of HFRS development. This review summarizes the main characteristics and influencing factors pertaining to the epidemic process of HFRS, so as to provide insights into effective prevention and control of this infectious disease.
肾综合征出血热（HFRS）是由汉坦病毒引起的乙类传染病，可导致急性肾损伤，死亡率高，在中国，肾综合征出血热的防控工作一直受到高度重视。研究发现，汉坦病毒类型与宿主选择性转变和区域适应性密切相关，并以基因重组的形式不断进化。肾综合征出血热的严重程度因汉坦病毒类型而异。此外，全球环境变化和宿主动物行为改变加速了汉坦病毒基因组变异，大规模土地开垦和基础设施建设增加了人类与宿主及疾病传播媒介接触的可能性，从而增加了肾综合征出血热发病的风险。本文综述了肾综合征出血热流行过程的主要特征和影响因素，以期为有效防控这种传染病提供思路。
