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乳制品摄入与男性和女性的脊柱小梁骨评分无关:弗雷明汉骨质疏松症研究。

Dairy food intake is not associated with spinal trabecular bone score in men and women: the Framingham Osteoporosis Study.

机构信息

Department of Medicine, Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Beth Israel Deaconess Medical Center and Harvard Medical School, 1200 Centre Street, Boston, MA, 02131, USA.

出版信息

Nutr J. 2022 May 10;21(1):26. doi: 10.1186/s12937-022-00781-1.

Abstract

BACKGROUND

Previous studies reported that dairy foods are associated with higher areal bone mineral density (BMD) in older adults. However, data on bone texture are lacking. We determined the association of dairy food intake (milk, yogurt, cheese, milk + yogurt and milk + yogurt + cheese) with spinal trabecular bone score (TBS).

METHODS

In this cross-sectional study, a validated semi-quantitative food frequency questionnaire was used to assess dairy food intake (servings/wk). TBS, an analysis of bone texture, was calculated from dual energy X-ray absorptiometry (DXA) scans. Sex-specific multivariable linear regression was used to estimate the association of dairy food intake (energy adjusted via residual methods) with each bone measure adjusting for covariates.

RESULTS

Mean age of 4,740 participants was 49 (SD: 13) years and mean milk + yogurt + cheese intake was 10.1 (SD: 8.4) servings/week in men and 10.9 (SD: 8.0) servings/week in women. There were no associations between dairy food intake and spinal TBS in adjusted models.

CONCLUSIONS

In this cohort of primarily healthy adults, dairy intake was not associated with bone texture.

摘要

背景

先前的研究报告称,乳制品与老年人更高的面积骨密度(BMD)有关。然而,关于骨纹理的数据却很缺乏。我们确定了乳制品摄入(牛奶、酸奶、奶酪、牛奶+酸奶和牛奶+酸奶+奶酪)与脊柱小梁骨评分(TBS)之间的关联。

方法

在这项横断面研究中,使用经过验证的半定量食物频率问卷来评估乳制品的摄入量(份/周)。TBS 是一种骨纹理分析,通过双能 X 射线吸收法(DXA)扫描来计算。采用多变量线性回归模型,根据性别调整乳制品的摄入量(通过残差法进行能量调整),并根据协变量调整与每个骨测量值的关联。

结果

4740 名参与者的平均年龄为 49(标准差:13)岁,男性牛奶+酸奶+奶酪的平均摄入量为 10.1(标准差:8.4)份/周,女性为 10.9(标准差:8.0)份/周。在调整后的模型中,乳制品的摄入与脊柱 TBS 之间没有关联。

结论

在这个主要由健康成年人组成的队列中,乳制品的摄入量与骨纹理无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b06/9092785/d93211acd523/12937_2022_781_Fig1_HTML.jpg

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