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近期用于合成环戊并[]吲哚的金属催化方法。

Recent metal-catalysed approaches for the synthesis of cyclopenta[]indoles.

作者信息

Vivekanand Thavaraj, Satpathi Bishnupada, Bankar Siddheshwar K, Ramasastry S S V

机构信息

Organic Synthesis and Catalysis Lab, Department of Chemical Sciences, Indian Institute of Science Education and Research (IISER) Mohali Knowledge City, Sector 81, S. A. S. Nagar Manauli PO Punjab 140306 India http://14.139.227.202/faculty/sastry/

出版信息

RSC Adv. 2018 May 22;8(33):18576-18588. doi: 10.1039/c8ra03480j. eCollection 2018 May 17.

Abstract

The cyclopenta[]indole scaffold is ubiquitously present in several bioactive natural products and pharmaceutically interesting compounds. Of the numerous methods known for the synthesis of cyclopenta-fused indoles, this review highlights only the metal-catalysed approaches reported from the year 2015 onwards. This review encompasses our own efforts leading to the synthesis of cyclopentannulated indoles, in addition to the seminal contributions of several other researchers.

摘要

环戊并[]吲哚骨架广泛存在于多种生物活性天然产物和具有药学意义的化合物中。在众多已知的环戊并稠合吲哚合成方法中,本综述仅重点介绍了2015年以来报道的金属催化方法。除了其他几位研究人员的开创性贡献外,本综述还涵盖了我们自己在环戊并吲哚合成方面所做的工作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0b4/9080641/1a7fca0597bb/c8ra03480j-f1.jpg

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