Wu Bing, Zhao Lijuan, Wang Ying, Dong Haotian, Yu Hua
Key Laboratory of Weak-Light Nonlinear Photonics, Ministry of Education, School of Physics, Nankai University Tianjin 300071 China
TEDA Institute of Biological Sciences and Biotechnology, Nankai University 23 Hongda Street, TEDA Tianjin 300457 China.
RSC Adv. 2019 Dec 19;9(72):42228-42235. doi: 10.1039/c9ra08447a. eCollection 2019 Dec 18.
We report β-PbF:Er/Yb nanocrystals (NCs) modified with 6-aminocaproic acid (6AA) wet chemical etching of glass ceramics (GCs). NCs body-doped with trivalent rare-earth (RE) ions were released from the GCs by etching of the glass matrix and modified with bifunctional 6AA ligands to enhance their water solubility. They have good stability in water with an average diameter of 56 nm and display efficient green (521, 550 nm) and red (660 nm) emission under the excitation of a 940 nm laser. High absolute sensitivity ( ) and relative sensitivity ( ) (0.0027 K and 1.18% K, respectively) and high resolution (0.25 K) were achieved for temperature sensing in the biological temperature range, using the fluorescence intensity ratio (FIR) technique. All of the experimental results indicate that the Er/Yb co-doped NCs modified with 6AA may potentially be useful as fluorescent biological temperature sensors.
我们报道了用6-氨基己酸（6AA）对β-PbF:Er/Yb纳米晶体（NCs）进行修饰以及对玻璃陶瓷（GCs）进行湿化学蚀刻的研究。通过蚀刻玻璃基质从GCs中释放出体掺杂三价稀土（RE）离子的NCs，并用双功能6AA配体对其进行修饰以提高其水溶性。它们在水中具有良好的稳定性，平均直径为56 nm，并在940 nm激光激发下表现出高效的绿色（521、550 nm）和红色（660 nm）发射。使用荧光强度比（FIR）技术，在生物温度范围内进行温度传感时，实现了高绝对灵敏度（ ）和相对灵敏度（ ）（分别为0.0027 K和1.18% K）以及高分辨率（0.25 K）。所有实验结果表明，用6AA修饰的Er/Yb共掺杂NCs可能有潜力用作荧光生物温度传感器。
