Public Health, Department of Social Medicine, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan.
Department of Public Health, Kindai University Faculty of Medicine, Osakasayama 589-8511, Japan.
Age Ageing. 2022 May 1;51(5). doi: 10.1093/ageing/afac080.
this study explored whether the modification of selected lifestyles is likely to increase life expectancy from middle age onwards, regardless of the presence of major comorbidities.
we examined a prospective cohort of 20,373 men and 26,247 women aged 40-80 years. Eight modifiable lifestyle factors were assessed: consumption of fruit, fish and milk, walking and/or sports participation, body-mass index, smoking status, alcohol consumption and sleep duration. Modifiable healthy lifestyle factors scored one point each, for a maximum of eight points. The impact of modifiable healthy lifestyle adoption on lifetime gain during the ages of 40-102 years was analysed.
during the median 21 years of follow-up, 8,966 individuals (3,683 men and 5,283 women) died. Life expectancy at 40 years (95% confidence intervals) for 7-8 health lifestyle points was 46.8 (45.6-48.1) and 51.3 (50.0-52.6) years for men and women, respectively. The potential impact of modifiable healthy lifestyle adoption on lifetime gain persisted over the age of 80 years or more, in individuals with ≥5 factors (P < 0.001), particularly older men. The benefits were more pronounced among patients with major comorbidities, such as cardiovascular disease, cancer, hypertension, diabetes, kidney disease and those with multimorbidity throughout all age categories.
adopting modifiable healthy lifestyles was associated with lifetime gain, even in individuals aged 80 years or more, regardless of the presence of any major comorbidities in each life stage since middle age. The findings imply the importance of improving the one's lifestyle for an increased lifespan, even among older patients and/or those with multimorbidity.
本研究旨在探讨在存在或不存在重大合并症的情况下,改变某些生活方式是否有可能延长从中年开始的预期寿命。
我们检查了一个前瞻性队列,包括 20373 名男性和 26247 名 40-80 岁的女性。评估了 8 种可改变的生活方式因素:水果、鱼和牛奶的摄入、步行和/或运动参与、体重指数、吸烟状况、饮酒量和睡眠时间。可改变的健康生活方式因素各计 1 分,最高分为 8 分。分析了从中年到 102 岁期间采用可改变的健康生活方式对终生收益的影响。
在中位 21 年的随访期间,有 8966 人(3683 名男性和 5283 名女性)死亡。对于 7-8 个健康生活方式点,40 岁时的预期寿命(95%置信区间)分别为男性 46.8(45.6-48.1)和女性 51.3(50.0-52.6)。在年龄超过 80 岁或以上的人群中,尤其是老年男性中,采用可改变的健康生活方式对终生收益的潜在影响持续存在(P<0.001)。在患有心血管疾病、癌症、高血压、糖尿病、肾病和在所有年龄段都有多发性疾病的患者中,这种益处更为明显。
即使在 80 岁或以上的人群中,采用可改变的健康生活方式与终生收益相关,无论在中年以后的每个生命阶段是否存在任何重大合并症。这些发现意味着,即使是老年患者和/或患有多种疾病的患者,改善生活方式对于延长寿命也很重要。