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[Effect of autologous marrow transplantation on bone marrow recovery following large-field fractionated irradiation of dogs].

作者信息

Strelin G S, Klestova O V, Sil'chenko N N, Stanzhevskaia T I

出版信息

Radiobiologiia. 1987 Mar-Apr;27(2):231-4.

PMID:3554320
Abstract

After large-field fractionated irradiation of dogs at a cumulative dose of 54 Gy, a stable bone marrow depletion occurs persisting for a year following irradiation. The automyelotransplantation after the end of the exposure elicits a transient recovery of the exposed bone marrow, 1.5-2 months after the beginning of irradiation, followed by a secondary depletion of the exposed haemopoietic sites. The control and the automyelotransplanted animals exhibited bone marrow recovery one year and six months after irradiation, respectively, the cellularity being maintained at a high level for 3 years of observation.

摘要

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