在使用钇玻璃微球进行放射性节段切除术时，空间密度和肿瘤剂量测定很重要。 - Suppr

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超能文献

Spatial density and tumor dosimetry are important in radiation segmentectomy with Y glass microspheres.

作者信息

Chiesa Carlo, Mazzaglia Stefania, Maccauro Marco

机构信息

Nuclear Medicine, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.

出版信息

Eur J Nucl Med Mol Imaging. 2022 Sep;49(11):3607-3609. doi: 10.1007/s00259-022-05819-4.

DOI:10.1007/s00259-022-05819-4

PMID:35543732

Abstract

摘要

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Spatial density and tumor dosimetry are important in radiation segmentectomy with Y glass microspheres.在使用钇玻璃微球进行放射性节段切除术时，空间密度和肿瘤剂量测定很重要。

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Calculation of tumour and normal tissue biological effective dose in Y liver radioembolization with different dosimetric methods.采用不同剂量学方法计算Y型肝脏放射性栓塞术中肿瘤及正常组织的生物等效剂量

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Radioembolization of hepatocellular carcinoma with Y glass microspheres: an earlier administration day unexpectedly improves tumour control probability.用钇玻璃微球进行肝细胞癌的放射性栓塞：意外提前给药日可提高肿瘤控制概率。

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Achieving Complete Pathologic Necrosis in Hepatocellular Carcinoma Treated with Radiation Segmentectomy before Liver Transplantation: A Comprehensive Glass Microsphere Analysis.肝移植前放射节段切除术治疗肝细胞癌实现完全病理坏死：全面玻璃微球分析

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本文引用的文献

Hepatocellular carcinoma radiation segmentectomy treatment intensification prior to liver transplantation increases rates of complete pathologic necrosis: an explant analysis of 75 tumors.肝癌放射亚段切除术治疗强化在肝移植前增加了完全病理坏死的发生率：75 个肿瘤的离体分析。

Eur J Nucl Med Mol Imaging. 2022 Sep;49(11):3892-3897. doi: 10.1007/s00259-022-05776-y. Epub 2022 Apr 20.

Radioembolization of Hepatocellular Carcinoma with Y Glass Microspheres: No Advantage of Voxel Dosimetry with Respect to Mean Dose in Dose-Response Analysis with Two Radiological Methods.用钇玻璃微球进行肝细胞癌的放射性栓塞：在两种放射学方法的剂量反应分析中，体素剂量测定相对于平均剂量无优势。

Cancers (Basel). 2022 Feb 15;14(4):959. doi: 10.3390/cancers14040959.

The number of microspheres in Y90 radioembolization directly affects normal tissue radiation exposure.钇-90放射性栓塞治疗中微球的数量直接影响正常组织的辐射暴露。

Eur J Nucl Med Mol Imaging. 2020 Apr;47(4):816-827. doi: 10.1007/s00259-019-04588-x. Epub 2019 Nov 18.

Clinical and dosimetric considerations for Y90: recommendations from an international multidisciplinary working group.钇 90 临床和剂量学考虑：来自一个国际多学科工作组的建议。

Eur J Nucl Med Mol Imaging. 2019 Jul;46(8):1695-1704. doi: 10.1007/s00259-019-04340-5. Epub 2019 May 16.

A Microdosimetric Analysis of Absorbed Dose to Tumor as a Function of Number of Microspheres per Unit Volume in 90Y Radioembolization.90Y放射性栓塞中肿瘤吸收剂量随单位体积微球数量变化的微剂量学分析。

J Nucl Med. 2016 Jul;57(7):1020-6. doi: 10.2967/jnumed.115.163444. Epub 2016 Feb 18.

Increased absorbed liver dose in Selective Internal Radiation Therapy (SIRT) correlates with increased sphere-cluster frequency and absorbed dose inhomogeneity.在选择性体内放射治疗（SIRT）中，肝脏吸收剂量增加与球体簇频率增加和吸收剂量不均匀性增加相关。

EJNMMI Phys. 2015 Dec;2(1):10. doi: 10.1186/s40658-015-0113-4. Epub 2015 Apr 25.

A hepatic dose-toxicity model opening the way toward individualized radioembolization planning.一种肝脏剂量毒性模型，为个体化放射性栓塞治疗计划开辟了道路。

J Nucl Med. 2014 Aug;55(8):1317-22. doi: 10.2967/jnumed.113.135301. Epub 2014 Jun 5.

The dosimetric importance of the number of 90Y microspheres in liver transarterial radioembolization (TARE).90Y微球数量在肝动脉放射性栓塞术（TARE）中的剂量学重要性。

Eur J Nucl Med Mol Imaging. 2014 Apr;41(4):634-8. doi: 10.1007/s00259-013-2674-6.

The low hepatic toxicity per Gray of 90Y glass microspheres is linked to their transport in the arterial tree favoring a nonuniform trapping as observed in posttherapy PET imaging.90Y 玻璃微球每格雷的低肝毒性与其在动脉树中的运输有关，这有利于非均匀捕获，正如治疗后 PET 成像所观察到的那样。

J Nucl Med. 2014 Jan;55(1):135-40. doi: 10.2967/jnumed.113.126839. Epub 2013 Dec 2.

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