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优化放射性栓塞肿瘤覆盖范围的技术。

Techniques to Optimize Radioembolization Tumor Coverage.

作者信息

Fassia M Kasim, Charalel Resmi Ann

机构信息

Division of Interventional Radiology, Department of Radiology, Weill Cornell Medicine, New York, New York.

Department of Population Health Sciences, Weill Cornell Medicine, New York, New York.

出版信息

Semin Intervent Radiol. 2024 Mar 14;41(1):16-19. doi: 10.1055/s-0043-1778659. eCollection 2024 Feb.

DOI:10.1055/s-0043-1778659
PMID:38495264
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10940038/
Abstract

Yttrium-90 (Y90) radioembolization has become a major locoregional treatment option for several primary and secondary liver cancers. Understanding the various factors that contribute to optimal tumor coverage including sphere count, embolization techniques, and catheter choice is important for all interventional radiologists while planning Y90 dosimetry and delivery. Here, we review these factors and the evidence supporting current practice paradigms.

摘要

钇-90(Y90)放射性栓塞已成为多种原发性和继发性肝癌的主要局部区域治疗选择。在规划Y90剂量测定和给药时,了解有助于实现最佳肿瘤覆盖的各种因素,包括微球数量、栓塞技术和导管选择,对所有介入放射科医生来说都很重要。在此,我们回顾这些因素以及支持当前实践模式的证据。

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Techniques to Optimize Radioembolization Tumor Coverage.优化放射性栓塞肿瘤覆盖范围的技术。
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本文引用的文献

1
Transarterial radioembolization: a systematic review on gaining control over the parameters that influence microsphere distribution.经动脉放射性栓塞术:对影响微球分布的参数进行控制的系统评价。
Drug Deliv. 2023 Dec;30(1):2226366. doi: 10.1080/10717544.2023.2226366.
2
Spatial density and tumor dosimetry are important in radiation segmentectomy with Y glass microspheres.在使用钇玻璃微球进行放射性节段切除术时,空间密度和肿瘤剂量测定很重要。
Eur J Nucl Med Mol Imaging. 2022 Sep;49(11):3607-3609. doi: 10.1007/s00259-022-05819-4.
3
Optimizing Y Particle Density Improves Outcomes After Radioembolization.优化 Y 粒子密度可改善放射性栓塞治疗后的结果。
Cardiovasc Intervent Radiol. 2022 Jul;45(7):958-969. doi: 10.1007/s00270-022-03139-6. Epub 2022 Apr 22.
4
Antireflux catheter improves tumor targeting in liver radioembolization with resin microspheres.反流导管可提高树脂微球肝动脉化疗栓塞术的肿瘤靶向性。
Diagn Interv Radiol. 2021 Nov;27(6):768-773. doi: 10.5152/dir.2021.20785.
5
Use of an anti-reflux catheter to improve tumor targeting for holmium-166 radioembolization-a prospective, within-patient randomized study.使用反流导管改善钬-166 放射性栓塞的肿瘤靶向作用:一项前瞻性、患者内随机研究。
Eur J Nucl Med Mol Imaging. 2021 May;48(5):1658-1668. doi: 10.1007/s00259-020-05079-0. Epub 2020 Oct 31.
6
The Efficacy of Coil Embolization to Obtain Intrahepatic Redistribution in Radioembolization: Qualitative and Quantitative Analyses.线圈栓塞在放射性栓塞中实现肝内血流再分布的疗效:定性和定量分析
Cardiovasc Intervent Radiol. 2020 Nov;43(11):1733-1734. doi: 10.1007/s00270-020-02618-y. Epub 2020 Aug 16.
7
The number of microspheres in Y90 radioembolization directly affects normal tissue radiation exposure.钇-90放射性栓塞治疗中微球的数量直接影响正常组织的辐射暴露。
Eur J Nucl Med Mol Imaging. 2020 Apr;47(4):816-827. doi: 10.1007/s00259-019-04588-x. Epub 2019 Nov 18.
8
Immune landscape of hepatocellular carcinoma microenvironment: Implications for prognosis and therapeutic applications.肝细胞癌微环境的免疫景观:对预后和治疗应用的影响。
Liver Int. 2019 Sep;39(9):1608-1621. doi: 10.1111/liv.14192. Epub 2019 Jul 28.
9
History and Evolution of Yttrium-90 Radioembolization for Hepatocellular Carcinoma.钇-90放射性栓塞治疗肝细胞癌的历史与演变
J Clin Med. 2019 Jan 7;8(1):55. doi: 10.3390/jcm8010055.
10
Tumor Targeting and Three-Dimensional Voxel-Based Dosimetry to Predict Tumor Response, Toxicity, and Survival after Yttrium-90 Resin Microsphere Radioembolization in Hepatocellular Carcinoma.肿瘤靶向及基于三维体素的剂量测定法预测钇-90树脂微球放射性栓塞治疗肝细胞癌后的肿瘤反应、毒性及生存率
J Vasc Interv Radiol. 2018 Dec;29(12):1662-1670.e4. doi: 10.1016/j.jvir.2018.07.006. Epub 2018 Sep 11.