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儿童和青少年感染 SARS-CoV-2:巴西的经验。

SARS-CoV-2 infection in children and adolescents: a Brazilian experience.

机构信息

Universidade de Taubaté, Taubaté, SP, Brazil.

Faculdade de Engenharia, Universidade Estadual Paulista "Júlio de Mesquita Filho", Guaratinguetá, SP, Brazil.

出版信息

Rev Paul Pediatr. 2022 May 6;40:e2021172. doi: 10.1590/1984-0462/2022/40/2021172IN. eCollection 2022.

Abstract

OBJECTIVE

To describe clinical and epidemiological aspects of children and adolescents infected with the SARS-CoV-2 in the Municipality of Taubaté, SP, from March to November 2020.

METHODS

Cross-sectional study with secondary data obtained from the Epidemiological Surveillance System about confirmed cases in city residents and from medical records of patients who were treated in hospitals in Taubaté, aged between 0 and 19 years. Chi-square and Student's t tests were used for comparisons.

RESULTS

677 cases in the studied age range were reported during the study period, corresponding to 10.1% of cases reported in the municipality. The rapid antibody test was the most used to confirm infection, followed by RT-PCR and serology. Symptoms were described in 57.7% of the cases, mainly fever and cough. Diarrhea was associated with age below 4 years, while fever, cough, headache, odynophagia, ageusia, anosmia, myalgia, and dyspnea were associated with an age ranging from 10 to 19 years. In the study period, there were no deaths from COVID-19 of residents of the municipality in the age group from 0 to 19 years.

CONCLUSIONS

The study was able to identify the proportion of involvement of COVID-19 in children and adolescents in the city, and the disease had a mild evolution. The main symptoms were fever and cough, but mainly diarrhea in younger children, and headache, odynophagia, anosmia, ageusia, and myalgia in adolescents.

摘要

目的

描述 2020 年 3 月至 11 月期间,来自 SP 州 Taubaté 市感染 SARS-CoV-2 的儿童和青少年的临床和流行病学方面。

方法

横断面研究,使用从城市居民传染病监测系统中获得的确诊病例的二级数据和在 Taubaté 医院接受治疗的患者的病历进行研究,年龄在 0 至 19 岁之间。使用卡方检验和学生 t 检验进行比较。

结果

在研究期间报告了 677 例研究年龄范围内的病例,占该市报告病例的 10.1%。最常用于确认感染的是快速抗体检测,其次是 RT-PCR 和血清学。57.7%的病例描述了症状,主要是发热和咳嗽。腹泻与年龄<4 岁有关,而发热、咳嗽、头痛、咽痛、味觉丧失、嗅觉丧失、肌痛和呼吸困难与 10 至 19 岁年龄组有关。在研究期间,该市 0 至 19 岁居民中没有 COVID-19 死亡病例。

结论

本研究能够确定 COVID-19 在该市儿童和青少年中的参与比例,且疾病具有轻度演变。主要症状是发热和咳嗽,但主要是腹泻在较小的儿童,以及头痛、咽痛、嗅觉丧失、味觉丧失和肌痛在青少年中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65c0/9095058/910921dc0c0d/1984-0462-rpp-40-e2021172-gf01.jpg

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