Department of Preventive Medicine and Health Education, School of Public Health, Fudan University, 138 Yixueyuan Road, Shanghai, 200032, China.
Songjiang Center of Disease Prevention and Control, Shanghai, 201620, China.
BMC Geriatr. 2022 May 11;22(1):414. doi: 10.1186/s12877-022-03074-8.
Metabolic Syndrome (MetS) is a common health problem among older adults. Previous studies have revealed the relationship between sleep duration as well as global sleep status and MetS.
This study aims to examine the association between the specific sleep characteristic and MetS as well as MetS components among community-dwelling old adults.
This cross-sectional study included 1499 community residents aged ≥ 60 years. Sleep characteristics were assessed using the Pittsburgh Sleep Quality Index (PSQI) and bed/rise time of the residents. Logistic regression analysis and multiple linear regression analysis were used to examine the associations between sleep characteristics and MetS as well as MetS components. A generalized additive model was built to assess the smooth relationship between triglyceride (TG) levels and sleep duration.
Of the 1499 participants, 449 (30.0%) had MetS, and 443 (29.6%) had poor sleep quality. The rise time was found to be associated with MetS (> 6:00 vs. 5:00 ~ 6:00: adjusted OR (95%) = 1.77 (1.17-2.69), P = 0.007). For the MetS components, a U-shaped relationship was first revealed for sleep duration and TG levels (EDF = 1.85, P < 0.001). Furthermore, significant associations also included the associations of subjective sleep quality and daytime dysfunction with hypertension, the associations of sleep efficiency and rise time with hyperglycemia, the associations of rise time with TG levels, and the association of bedtime with waist circumference.
The different sleep characteristics were associated with different MetS components.
代谢综合征（MetS）是老年人常见的健康问题。既往研究揭示了睡眠时间和整体睡眠状况与 MetS 的关系。
本研究旨在探讨社区老年人特定睡眠特征与 MetS 及其组分的关系。
本横断面研究纳入了 1499 名年龄≥60 岁的社区居民。使用匹兹堡睡眠质量指数（PSQI）和居民的卧床/起床时间评估睡眠特征。采用 logistic 回归分析和多元线性回归分析来检验睡眠特征与 MetS 及其组分的关系。构建广义加性模型来评估甘油三酯（TG）水平与睡眠时间之间的平滑关系。
在 1499 名参与者中，449 名（30.0%）患有 MetS，443 名（29.6%）睡眠质量差。起床时间与 MetS 相关（>6:00 比 5:006:00：调整后的 OR（95%）=1.77（1.172.69），P=0.007）。对于 MetS 组分，首次揭示了睡眠时间与 TG 水平之间的 U 型关系（EDF=1.85，P<0.001）。此外，还存在显著关联，包括主观睡眠质量和日间功能障碍与高血压相关，睡眠效率和起床时间与高血糖相关，起床时间与 TG 水平相关，以及就寝时间与腰围相关。
不同的睡眠特征与不同的 MetS 组分相关。
