Sirohiya Prashant, Vig Saurabh, Pandey Khushboo, Meena Jitendra K, Singh Ram, Ratre Brajesh K, Kumar Balbir, Pandit Anuja, Bhatnagar Sushma
Onco-Anaesthesia and Palliative Medicine, All India Institute of Medical Sciences, New Delhi, IND.
Preventive Oncology, All India Institute of Medical Sciences, New Delhi, IND.
Cureus. 2022 Apr 10;14(4):e24005. doi: 10.7759/cureus.24005. eCollection 2022 Apr.
Background and objective It has been observed that peripheral oxygen saturation (SpO) measured by pulse oximeter is consistently lower than arterial oxygen saturation (SaO) measured directly by blood gas analysis. In this study, we aimed to evaluate the correlation between SpO and SaO, and SpO and partial pressure of oxygen (PaO), and compare the SpO/FiO(SF) and PaO/FiO(PF) ratios in patients with coronavirus disease 2019 (COVID-19). Methods In this observational study, SpO was recorded and arterial blood gas analysis was performed among 70 COVID-19 patients presenting on room air (FiO= 0.21). SaO and PaO were recorded from arterial blood gas analysis. The SF and PF ratios were then calculated. Results The strength of correlations between SpO and SaO, and SpO and PaO, were significant (p<0.001) and moderately positive [Pearson coefficient (r) = 0.68, 0.53]. SpO value (85%), i.e., SF ratio (404.7 or below), was the best estimate for mild ARDS (acute respiratory distress syndrome) [PF ratio (300 or below)] with a sensitivity of 80.6% and specificity of 53%. Conclusion A pulse oximeter is a vital tool in the diagnosis and management of COVID-19. In our study, SpO was found to have a positive correlation with SaO and PaO with acceptable sensitivity but low specificity in estimating mild ARDS. Therefore, pulse oximetry can be used as a tool for the early diagnosis of mild COVID-19 ARDS as per the given considerations and clinical correlation.
背景与目的 据观察，通过脉搏血氧仪测量的外周血氧饱和度（SpO）始终低于通过血气分析直接测量的动脉血氧饱和度（SaO）。在本研究中，我们旨在评估SpO与SaO之间的相关性，以及SpO与氧分压（PaO）之间的相关性，并比较2019冠状病毒病（COVID-19）患者的SpO/FiO（SF）和PaO/FiO（PF）比值。方法 在这项观察性研究中，对70例接受室内空气（FiO = 0.21）的COVID-19患者记录SpO并进行动脉血气分析。从动脉血气分析中记录SaO和PaO。然后计算SF和PF比值。结果 SpO与SaO之间以及SpO与PaO之间的相关性强度显著（p<0.001）且呈中度正相关[皮尔逊系数（r）= 0.68，0.53]。SpO值（85%），即SF比值（404.7或更低），是轻度急性呼吸窘迫综合征（ARDS）[PF比值（300或更低）]的最佳估计值，敏感性为80.6%，特异性为53%。结论 脉搏血氧仪是COVID-19诊断和管理中的重要工具。在我们的研究中，发现SpO与SaO和PaO呈正相关，在估计轻度ARDS时具有可接受的敏感性但特异性较低。因此，根据给定的考虑因素和临床相关性，脉搏血氧测定法可作为早期诊断轻度COVID-19 ARDS的工具。
