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中国温州在校学生的尿液筛查及9年病历系统随访

Urine Screening and 9 Years' Medical Record System Follow-Up Among School Students in Wenzhou, China.

作者信息

Chen Tingting, Yang Qing, Xu Hong, Gong Yinv, Guo Xiaoling, Lin Hongzhou, Yang Jianhuan, Zhuang Jieqiu, Lan Junwei, Chu Maoping, Wang Dexuan

机构信息

Department of Pediatrics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.

Basic Medical Research Center, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.

出版信息

Front Pediatr. 2022 Apr 25;10:862029. doi: 10.3389/fped.2022.862029. eCollection 2022.

DOI:10.3389/fped.2022.862029
PMID:35547544
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9081790/
Abstract

School urinary screening programming can be useful for the early detection of renal and urinary disorders. However, urine screening is not included in the school health check-up in our region. Therefore, from February 2012 to March 2021, 12,497 school students were screened for urinalysis, and a long-term follow-up took place an electronic medical record system. Among these screened students, 719 (5.75%) positive individuals received a repeat urinalysis 2 weeks later. During the 9-year medical record system follow-up period, 5 children had renal biopsies and 2 children had a diagnosis of IgA nephropathy (IgAN), while the remaining 3 children were diagnosed with thin basement membrane disease (TBM), primary nephrotic syndrome (PNS), and were suspected of C3 glomerulopathy, respectively. By this, calling for the school urine screening program as a physical examination item for primary and secondary school-aged students will contribute to enabling early detection of urine abnormalities and allow for early treatment.

摘要

学校尿液筛查项目有助于早期发现肾脏和泌尿系统疾病。然而,我们地区的学校健康检查中不包括尿液筛查。因此,在2012年2月至2021年3月期间,对12497名在校学生进行了尿液分析筛查,并通过电子病历系统进行了长期随访。在这些接受筛查的学生中,719名(5.75%)阳性个体在2周后接受了复查尿液分析。在9年的病历系统随访期间,5名儿童进行了肾活检,2名儿童被诊断为IgA肾病(IgAN),其余3名儿童分别被诊断为薄基底膜病(TBM)、原发性肾病综合征(PNS),并疑似C3肾小球病。由此可见,将学校尿液筛查项目作为中小学生的体检项目,将有助于早期发现尿液异常并实现早期治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3560/9081790/54fd41ca80de/fped-10-862029-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3560/9081790/54fd41ca80de/fped-10-862029-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3560/9081790/54fd41ca80de/fped-10-862029-g001.jpg

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本文引用的文献

1
Uptake of further investigations following universal urinary screening among elementary and junior high school students in Shiga Prefecture, Japan: A retrospective cohort study.日本滋贺县中小学生普遍进行尿液筛查后的进一步检查情况:一项回顾性队列研究。
Nephrology (Carlton). 2020 Aug;25(8):599-606. doi: 10.1111/nep.13710. Epub 2020 Mar 20.
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Distribution of glomerular diseases in Taiwan: preliminary report of National Renal Biopsy Registry-publication on behalf of Taiwan Society of Nephrology.台湾地区肾小球疾病的分布:国家肾脏活检登记处初步报告——代表台湾肾脏病学会发表
BMC Nephrol. 2018 Jan 10;19(1):6. doi: 10.1186/s12882-017-0810-4.
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Urinary Screening for Early Detection of Kidney Diseases.
尿筛检测早期肾脏病。
Indian J Pediatr. 2018 Aug;85(8):607-612. doi: 10.1007/s12098-017-2494-y. Epub 2017 Nov 23.
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A nationwide study of mass urine screening tests on Korean school children and implications for chronic kidney disease management.一项针对韩国学童的全国性大规模尿液筛查检测研究及其对慢性肾脏病管理的意义。
Clin Exp Nephrol. 2013 Apr;17(2):205-10. doi: 10.1007/s10157-012-0672-9. Epub 2012 Nov 8.
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Pediatrics. 2010 Apr;125(4):660-3. doi: 10.1542/peds.2009-1980. Epub 2010 Mar 15.
9
Chronic kidney disease perspectives in Japan and the importance of urinalysis screening.日本慢性肾脏病的现状及尿液分析筛查的重要性
Clin Exp Nephrol. 2008 Feb;12(1):1-8. doi: 10.1007/s10157-007-0010-9. Epub 2008 Jan 5.
10
School urinalysis screening in Korea.韩国的学校尿液分析筛查。
Nephrology (Carlton). 2007 Dec;12 Suppl 3:S3-7. doi: 10.1111/j.1440-1797.2007.00873.x.