Division of Hematology, Mayo Clinic, Rochester, MN, USA.
Leuk Lymphoma. 2022 Oct;63(10):2422-2427. doi: 10.1080/10428194.2022.2074993. Epub 2022 May 12.
There is increasing evidence that social infrastructure and a healthy social network can improve cancer survival. Mayo Clinic has an outpatient stem cell transplantation program for myeloma. Safe outpatient transplantation requires a caregiver to be present. Patients lacking a caregiver are transplanted as an inpatient. We reviewed outcomes on over 2000 patients with multiple myeloma, 2103 transplanted as an outpatient compared with 41 hospitalized for transplantation. Although progression-free survival following transplantation was identical between the two groups, overall survival was shorter in those hospitalized. This suggests that the absence of a caregiver for transplantation is an important surrogate of the social infrastructure associated with poor outcomes in transplanted patients with multiple myeloma.
越来越多的证据表明，社会基础设施和健康的社交网络可以改善癌症患者的生存率。梅奥诊所（Mayo Clinic）有一个多发性骨髓瘤的门诊干细胞移植项目。安全的门诊移植需要有护理人员在场。没有护理人员的患者则作为住院患者进行移植。我们回顾了 2000 多名多发性骨髓瘤患者的结果，其中 2103 名患者作为门诊患者进行移植，41 名患者住院进行移植。尽管两组患者在移植后的无进展生存率相同，但住院患者的总生存率较低。这表明，移植时没有护理人员，这是与多发性骨髓瘤移植患者不良预后相关的社会基础设施缺失的一个重要替代指标。
