Urbach A H, Gartner J C, Malatack J J, Zitelli B J, Iwatsuki S, Shaw B W, Starzl T E
Am J Dis Child. 1987 May;141(5):547-9. doi: 10.1001/archpedi.1987.04460050089037.
The linear growth of 29 patients was evaluated from two to 41/2 years after liver transplantation. All patients received cyclosporine and low-dose prednisone. Eight patients (28%) displayed acceleration of linear growth velocity and were above the fifth percentile at the end of the evaluation period. Four patients (14%) grew normally prior to transplantation and continued to grow normally after the surgical procedure. Only four patients (14%) dropped from higher levels to below the fifth percentile. Thirteen patients (45%) were less than the fifth percentile before and after surgery; ten of these 13 patients have attained normal or accelerated growth velocity. Good linear growth has been achieved in more than three fourths of patients who underwent liver transplantation.
对29例患者肝移植后2年至4年半的线性生长情况进行了评估。所有患者均接受环孢素和低剂量泼尼松治疗。8例患者(28%)线性生长速度加快,在评估期末高于第五百分位数。4例患者(14%)移植前生长正常,手术后继续正常生长。只有4例患者(14%)从较高水平降至第五百分位数以下。13例患者(45%)手术前后均低于第五百分位数;这13例患者中有10例已达到正常或加速生长速度。超过四分之三接受肝移植的患者实现了良好的线性生长。