School of Speech-Language Pathology and Audiology, Université de Montréal, Montreal, Canada.
Center of Research on Brain, Language and Music (CRBLM), Montreal, Canada.
Int J Audiol. 2023 Jun;62(6):489-499. doi: 10.1080/14992027.2022.2070083. Epub 2022 May 12.
Hyperacusis is known as a reduced tolerance to sounds perceived as normal to the majority of the population. There is currently no agreed definition, diagnostic tool, or objective measure of its occurrence. The purpose of this review is to catalogue the research to date on the use of auditory evoked potentials (AEP) to assess hyperacusis.
A step-by-step methodology was conducted following guidelines. Four databases were searched. A total of 3343 papers were identified. A final yield of 35 articles were retained for analysis.
The analysis identified four types of aetiologies to describe the hyperacusic population in AEP studies; developmental disorders ( = 19), neurological disorders ( = 3), induced hearing damage ( = 8) and idiopathic aetiology ( = 5). Electrophysiological measures were of short ( = 16), middle ( = 13) and long ( = 19) latencies, believed to reflect the activity of the ascending and descending pathways of the auditory system from periphery to cortex.
The results of this review revealed the potential use of electrophysiological measures for further understanding the mechanisms of hyperacusis. However, according to the disparity of concepts to define hyperacusis, definitions and populations need to be clarified before biomarkers specific to hyperacusis can be identified.
对大多数人来说正常的声音感知的耐受性降低被称为听觉过敏。目前尚无公认的定义、诊断工具或其发生的客观测量方法。本综述的目的是对迄今为止使用听觉诱发电位（AEPs）评估听觉过敏的研究进行分类。
按照指南进行了逐步的方法。共搜索了四个数据库。共确定了 3343 篇论文，最终有 35 篇文章被保留用于分析。
分析确定了在 AEPs 研究中描述听觉过敏人群的四种病因类型；发育障碍（ = 19）、神经障碍（ = 3）、诱发性听力损伤（ = 8）和特发性病因（ = 5）。电生理测量值的潜伏期较短（ = 16）、中等（ = 13）和较长（ = 19），据信反映了听觉系统从外围到皮层的上行和下行通路的活动。
本综述的结果表明，电生理测量具有进一步了解听觉过敏机制的潜力。然而，根据定义听觉过敏的概念差异，需要在确定特定于听觉过敏的生物标志物之前澄清定义和人群。
