Williams G, Billson F, Husain R, Howlader S A, Islam N, McClellan K
Br J Ophthalmol. 1987 Apr;71(4):315-21. doi: 10.1136/bjo.71.4.315.
Experience in setting up an inexpensive microbiology laboratory in the Bangladesh National Society for the Blind Eye Hospital and Training Complex at Chittagong is presented, together with the results of a pilot study to identify organisms responsible in 33 consecutive cases of suppurative keratitis in the Chittagong area of Bangladesh. Of the 33 cases 21 were positively identified by means of Gram stain and/or culture. Two-thirds of the responsible organisms were bacteria, and one-third were fungi. The bacterial causes included Streptococcus pneumoniae and Pseudomonas aeruginosa. The fungi isolated were Aspergillus fumigatus, Aspergillus ochraceus, and Fusarium solani. Among the causes of failure to diagnose the organism was chronicity of infection and previous treatment. The value of the study in the planning of future treatment regimens, and the implications of setting up similar relatively cheap microbiology laboratory facilities in developing countries, are discussed.
介绍了在吉大港市孟加拉国全国盲人眼医院及培训中心建立一个低成本微生物实验室的经验,以及一项初步研究的结果,该研究旨在确定孟加拉国吉大港市连续33例化脓性角膜炎病例中的致病微生物。在这33例病例中,有21例通过革兰氏染色和/或培养得到了明确诊断。三分之二的致病微生物为细菌,三分之一为真菌。细菌病因包括肺炎链球菌和铜绿假单胞菌。分离出的真菌有烟曲霉、赭曲霉和茄病镰刀菌。未能诊断出致病微生物的原因包括感染的慢性化和先前的治疗。讨论了该研究在未来治疗方案规划中的价值,以及在发展中国家建立类似相对廉价的微生物实验室设施的意义。