Scott J E
Br J Urol. 1987 Apr;59(4):291-6. doi: 10.1111/j.1464-410x.1987.tb04634.x.
Seven babies (six male, one female) with ureteric reflux, all of whom had antenatal renal dilatation, are described together with one other baby who was found to have gross ureteric reflux when investigated following an acute urinary infection at the age of 9 days. There was a strong probability that all of the babies had fetal ureteric reflux (FUR). Radioisotope studies demonstrated parenchymal damage in three of seven and reduced function in four of 10 refluxing kidneys. Subsequent investigation showed no increase in the areas of parenchymal damage but there was evidence that function in some kidneys had deteriorated. It was thought that this was due to disturbances in inter-renal or renal-child related growth velocities. A plea is put forward for more detailed postnatal examination of babies whose urinary tracts show evidence of dilatation antenatally.
描述了7名患有输尿管反流的婴儿(6名男性,1名女性),他们在产前均有肾积水,还描述了另外1名婴儿,该婴儿在9天龄时因急性尿路感染接受检查时被发现有严重的输尿管反流。所有这些婴儿极有可能患有胎儿输尿管反流(FUR)。放射性同位素研究显示,7名婴儿中有3名存在实质损害,10个反流肾脏中有4个功能减退。后续检查显示实质损害面积没有增加,但有证据表明一些肾脏的功能已经恶化。据认为,这是由于肾间或肾与儿童相关生长速度的紊乱所致。本文呼吁对产前尿路有扩张迹象的婴儿进行更详细的产后检查。