Kaplan E, Nickoloff B J
Clin Plast Surg. 1987 Apr;14(2):277-300.
A nevus is a cutaneous lesion characterized histologically by clustering and disorganization of a variety of cell types in the skin including the epidermis, appendages, melanocytes, and their precursor cells. Commonly, a nevus is congenital but it may be acquired. Owing to the prevalence and variations of melanocytic nevi and their association with malignancy, this article discusses the development, classification, histology, and clinical characteristics of nevi with an emphasis on the relationship to malignancy. Recommendations are provided for treatment of these benign lesions.
痣是一种皮肤病变,其组织学特征是皮肤中多种细胞类型(包括表皮、附属器、黑素细胞及其前体细胞)聚集和排列紊乱。通常,痣是先天性的,但也可能是后天获得的。由于黑素细胞痣的普遍性、变异性及其与恶性肿瘤的关联,本文讨论了痣的发生、分类、组织学和临床特征,重点是与恶性肿瘤的关系。并为这些良性病变的治疗提供了建议。