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阻塞性睡眠呼吸暂停严重程度与咬合参数:伴发疾病的成年患者的前瞻性研究。

OSAS Severity and Occlusal Parameters: A Prospective Study among Adult Subjects with Comorbidities.

机构信息

Department of Oral and Maxillo Facial Sciences, "Sapienza" University of Rome, 00161 Rome, Italy.

Department of Sensory Organs, "Sapienza" University of Rome, 00161 Rome, Italy.

出版信息

Int J Environ Res Public Health. 2022 May 1;19(9):5517. doi: 10.3390/ijerph19095517.

Abstract

INTRODUCTION

OSAS is an emerging public health problem. Early diagnosis in adults with comorbidities is the gold standard to avoid complications caused by a late diagnosis. The aim of the study, part of the SLeeP@SA project, was to identify within a population with dysmetabolic comorbidities the association of occlusal clinical signs, defined by orthodontic parameters, and of the anthropometric phenotype, with the severity of OSAS.

MATERIALS AND METHODS

A dedicated questionnaire containing questions regarding the presence of deep bite, augmented overjet, partial edentulism, and bruxism was completed by clinic staff. OSAS was evaluated using an unattended home PSG device, which recorded the AHI value. BMI and neck circumference were also measured. The Kolmogorov-Smirnov test was performed to evaluate the association of the AHI with occlusal clinical signs. The significance was set at ≤ 0.05. The association of AHI with BMI and neck circumference was evaluated with the Pearson correlation coefficient.

RESULTS

In total, 199 subjects were evaluated. No statistically significant association between occlusal parameters and AHI was found, while the AHI showed a positive correlation with BMI and neck circumference. The neck circumference seemed to be a better clinical predictor for OSAS severity than BMI, especially for females.

CONCLUSIONS

These results highlight how the orthodontic clinical data alone are not sufficient to establish an association between occlusal anomalies and OSAS severity, but further investigation involving a specialist orthodontic diagnosis is necessary.

摘要

简介

阻塞性睡眠呼吸暂停低通气综合征(OSAS)是一个新出现的公共卫生问题。在合并有并发症的成年人中进行早期诊断是避免因诊断延迟而导致并发症的金标准。该研究的目的是在患有代谢紊乱合并症的人群中,确定由正畸参数定义的咬合临床特征以及人体测量表型与 OSAS 严重程度之间的关联。

材料和方法

临床工作人员填写了一份专门的问卷,其中包含有关深覆合、上前牙过度萌出、部分牙列缺失和磨牙症存在的问题。使用无人值守的家庭 PSG 设备评估 OSAS,记录 AHI 值。还测量了 BMI 和颈围。采用 Kolmogorov-Smirnov 检验评估 AHI 与咬合临床特征的相关性。显著性水平设置为≤0.05。使用 Pearson 相关系数评估 AHI 与 BMI 和颈围的相关性。

结果

共评估了 199 名受试者。未发现咬合参数与 AHI 之间存在统计学显著相关性,而 AHI 与 BMI 和颈围呈正相关。颈围似乎比 BMI 更能准确预测 OSAS 严重程度,尤其是对女性而言。

结论

这些结果表明,仅通过正畸临床数据不足以确定咬合异常与 OSAS 严重程度之间的关联,需要进一步进行涉及专业正畸诊断的调查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fcd/9105419/62da6a313d6b/ijerph-19-05517-g001.jpg

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