使用近红外光谱神经反馈的认知训练可改善老年人的认知功能。

Cognitive Training with Neurofeedback Using fNIRS Improves Cognitive Function in Older Adults.

机构信息

Department of Psychological and Brain Sciences, University of California Santa Barbara, Santa Barbara, CA 93106, USA.

出版信息

Int J Environ Res Public Health. 2022 May 2;19(9):5531. doi: 10.3390/ijerph19095531.

This study examined the effects of a 4-week cognitive training program with neurofeedback (CT-NF) among 86 healthy adults (M = 66.34 years, range 54-84) randomized to either a treatment (app-based ABC games) or control (Tetris) group. Participants completed seven cognitive assessments, pre- and post-intervention, and measured their cortical brain activity using a XB-01 functional near-infrared spectroscopy (fNIRS) brain sensor, while engaging in CT-NF. The treatment (ABC) group showed significant (pre/post-intervention) improvements in memory (MEM), verbal memory (VBM), and composite cognitive function, while the control group did not. However, both groups showed significant improvements in processing speed (PS) and executive function (EF). In line with other studies, we found that strength of cortical brain activity (measured during CT-NF) was associated with both cognitive (pre and post) and game performance. In sum, our findings suggest that CT-NF and specifically ABC exercises, confer improved cognition in the domains of MEM, VBM, PS, and EF.

本研究调查了 86 名健康成年人（平均年龄为 66.34 岁，年龄范围为 54-84 岁）在接受为期 4 周的认知训练与神经反馈（CT-NF）后的效果，这些参与者被随机分配到治疗组（基于应用程序的 ABC 游戏）或对照组（俄罗斯方块）。参与者在干预前后完成了七项认知评估，并使用 XB-01 功能近红外光谱（fNIRS）脑传感器测量他们的皮质脑活动，同时进行 CT-NF。治疗组（ABC）在记忆（MEM）、言语记忆（VBM）和综合认知功能方面显示出显著的（干预前后）改善，而对照组则没有。然而，两组在处理速度（PS）和执行功能（EF）方面都有显著提高。与其他研究一致，我们发现皮质脑活动强度（在 CT-NF 期间测量）与认知（前后）和游戏表现都相关。总之，我们的发现表明，CT-NF 特别是 ABC 练习，可以改善 MEM、VBM、PS 和 EF 等认知领域的认知能力。