Xie Lei, Liu Yong, Gao Yuling, Zhou Jiaqi
The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Front Neurosci. 2024 Oct 2;18:1469903. doi: 10.3389/fnins.2024.1469903. eCollection 2024.
In recent years, with the aggravation of aging, the incidence of neurodegenerative diseases is increasing year by year, and the prognosis of patients is poor. Functional Near-Infrared Spectroscopy (fNIRS) is a new and non-invasive neuroimaging technology, which has been gradually deepened in the application research of neurodegenerative diseases by virtue of its unique neurooxygen signal brain functional imaging characteristics in monitoring the disease condition, making treatment plans and evaluating the treatment effect. In this paper, the mechanism of action and technical characteristics of fNIRS are briefly introduced, and the application research of fNIRS in different neurodegenerative diseases is summarized in order to provide new ideas for future related research and clinical application.
近年来，随着老龄化加剧，神经退行性疾病的发病率逐年上升，且患者预后较差。功能近红外光谱技术（fNIRS）是一种新型的非侵入性神经成像技术，凭借其在监测病情、制定治疗方案及评估治疗效果方面独特的神经氧信号脑功能成像特性，在神经退行性疾病的应用研究中不断深入。本文简要介绍了fNIRS的作用机制和技术特点，并总结了fNIRS在不同神经退行性疾病中的应用研究，以期为未来相关研究及临床应用提供新思路。
