Huang Junjie, Chan Wing Chung, Ngai Chun Ho, Lok Veeleah, Zhang Lin, Lucero-Prisno Don Eliseo, Xu Wanghong, Zheng Zhi-Jie, Elcarte Edmar, Withers Mellissa, Wong Martin C S
The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong 999077, China.
Department of Global Public Health, Karolinska Institute, Karolinska University Hospital, 171 77 Stockholm, Sweden.
Cancers (Basel). 2022 Apr 29;14(9):2230. doi: 10.3390/cancers14092230.
This study aimed to investigate the most updated worldwide incidence and mortality, risk factors, and epidemiologic trend of ovarian cancer in different countries, regions, and age groups. The database was used for incidence and mortality rates of ovarian cancer in 2020. Data from and the was accessed for trend analysis. Age-standardized rates (ASRs, per 100,000 persons) were calculated for incidence and mortality. The 10-year annual average percent change (AAPC) was estimated by Joinpoint regression analysis. There was an overall decreasing trend of ovarian cancer, yet its burden has been increasing in lower-income countries and among younger females in some countries. Intensive lifestyle modifications are warranted, especially for the populations at high risk for ovarian cancer, including smoking cessation, alcohol use reduction, physical activity, weight control, and treatment of metabolic diseases.
本研究旨在调查不同国家、地区和年龄组中卵巢癌的最新全球发病率、死亡率、危险因素及流行病学趋势。该数据库用于获取2020年卵巢癌的发病率和死亡率。从[具体来源1]和[具体来源2]获取数据进行趋势分析。计算发病率和死亡率的年龄标准化率(每10万人)。通过Joinpoint回归分析估计10年的年均变化百分比(AAPC)。卵巢癌总体呈下降趋势,但其负担在低收入国家以及一些国家的年轻女性中呈上升趋势。需要大力改变生活方式,特别是对于卵巢癌高危人群,包括戒烟、减少饮酒、体育锻炼、控制体重以及治疗代谢性疾病。