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体质量指数介导外出就餐频率与农村成年人高血压的关系:一项大规模横断面研究。

Body Mass Index Mediates the Relationship between the Frequency of Eating Away from Home and Hypertension in Rural Adults: A Large-Scale Cross-Sectional Study.

机构信息

Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.

出版信息

Nutrients. 2022 Apr 27;14(9):1832. doi: 10.3390/nu14091832.

Abstract

This study was conducted to investigate the association of eating away from home (EAFH) frequency with hypertension and to explore whether the association was mediated by BMI. A total of 29,611 participants were selected from the Henan Rural Cohort Study. Data on the frequency of EAFH were obtained by face-to-face questionnaires. The relationship between EAFH frequency and blood pressure was evaluated by linear regression. Logistic regression and restricted cubic spline were used to assess the association between EAFH frequency and hypertension, and the mediation effect of BMI on the relationship was performed. There were pronounced associations between the frequency of EAFH and blood pressure (P trend < 0.001) in the total population and men. Compared with the population with 0 times EAFH per week, the multivariate odds ratios (ORs) and 95% confidence intervals (95% CIs) for hypertension of the group with 7 times or more EAFH per week were 1.673 (1.482−1.889) for the total population and 1.634 (1.413−1.890) for men. A nonlinear dose-response relationship was detected between the frequency of EAFH and hypertension (p < 0.001), and the relationship was partially mediated by BMI. The proportion explained was 21.3% in the total population and 25.4% in men. The current study indicated that EAFH was associated with rising blood pressure and increased risk of hypertension and BMI partially mediated the relationship.

摘要

本研究旨在探讨外出就餐频率(EAFH)与高血压的关联,并探讨这种关联是否由 BMI 介导。本研究共纳入了 29611 名来自河南农村队列研究的参与者。通过面对面的问卷调查获取 EAFH 频率的数据。采用线性回归评估 EAFH 频率与血压之间的关系。采用逻辑回归和限制性立方样条分析 EAFH 频率与高血压之间的关联,并对 BMI 对这种关系的中介作用进行分析。在总人群和男性中,EAFH 频率与血压之间存在显著关联(P 趋势<0.001)。与每周 EAFH 频率为 0 次的人群相比,每周 EAFH 频率为 7 次或更多次的人群患高血压的多变量比值比(OR)及其 95%置信区间(95%CI)分别为总人群的 1.673(1.482-1.889)和男性的 1.634(1.413-1.890)。EAFH 频率与高血压之间存在非线性剂量反应关系(p<0.001),BMI 部分介导了这种关系。在总人群中,解释比例为 21.3%,在男性中为 25.4%。本研究表明,EAFH 与血压升高和高血压风险增加有关,BMI 部分介导了这种关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3035/9104948/e04456dd4b91/nutrients-14-01832-g001.jpg

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